ID   YR008_MIMIV             Reviewed;        1052 AA.
AC   Q5UP79;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Uncharacterized putative helicase R8;
DE            EC=3.6.4.-;
GN   OrderedLocusNames=MIMI_R8;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
CC   -!- SIMILARITY: Belongs to the mimivirus R1 family. {ECO:0000305}.
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DR   EMBL; AY653733; AAV50283.1; -; Genomic_DNA.
DR   PRIDE; Q5UP79; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003450; Replication_origin-bd.
DR   Pfam; PF02399; Herpes_ori_bp; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..1052
FT                   /note="Uncharacterized putative helicase R8"
FT                   /id="PRO_0000253255"
FT   DOMAIN          389..561
FT                   /note="Helicase ATP-binding"
FT   BINDING         400..407
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1052 AA;  123521 MW;  52525FBF229C0238 CRC64;
     MIKKIMKMAK IYKSKNAMID AVPVIDRESK MFLQYPVNSN GCCNFTVIDK DKDFFSNIKS
     TKSNSKFLQE MFIDGTKRKP YLDIEHYYPS EKEFKKDFKR IIPQIVNDII QVFAKEYDQV
     IKLSDVLLLN SSGQSSDGYK LSVHVVVSPK NKTFYYTNSK KIENNTAYHL YASLININSE
     YKDKENFNDK PHGYLDEQVY RKDATLRMIG SCKYPTGDRC LDPIDSKTLE KLDLTDKQKL
     NYLISYIDDT KPTILLETPI IQQTTISKTK IQHNEPTKTN INNKLLDLVK KYHPSAKQYG
     SSKEGYYNFN YDNRTEKCPL SGVTHDSNGF YVIEKSSGCF LKCYSKKCHG KSMHLGYVDE
     TDQFVDEAHQ INTKYLLQDP LVPKLLEDWI NKGKTFAIKS AMGTGKTYLI KHILDKYKLN
     KVLWITHRQT LTKSLYGSFK DYGFVSYMDT QNCLYQYDKV LVQIDSLMRI KEFDMFENKQ
     LVKKYDLVII DEIEGCLSHY ESPYLNKPDI DSRYIFNFMI DVIRFSNKLI VLDADISIRT
     QLFIEHIDKI TNKGGNYIMI NNSYQPITKT FTITNDEGDF DTKLFADIKA KKNICVVSMS
     AGAVNKIAVE LNKMGTKYVS HTSKSNDSLK KNLEDVNNFW KQQQVVMFSP SIISGIDFNE
     IHFDKMYCII KSGNKTCDPR SFLQMVGRIR HLGDQNIFCW YQQIPIFIDK TNKIIPKLQS
     DVYTFDDLLS YYRYYETLRN KKIIKNVVYE TVEGDDVISF VNKSVEIDLF DKISLHNEVE
     QLNKHQDVFL TVLNRLIMRA GNKIDFKLVL KDDKKPIMDK INNREEEINI MIDLDDSKYD
     IKELSTKQTN NQLTEIEKLF IKKYYFKKKL GIKKEIDKDK LRELMTKYMD KEYFIERYEI
     LFGYKKISDS NDDSKTKEKD RIKRKIIVDF VNILIGKHYN NCLNDSKLKR IIIKDDQYSK
     ALKKIIKESM YFSNEEKYRP LFRKKKGSLK SNPKKEKEIQ FYTSTLVRLL REYNIILKVE
     SRKKTNGKSS YLRSLSVDKQ IKDVVENKYN HQ