YR039_YEAST
ID YR039_YEAST Reviewed; 72 AA.
AC P0CD97; D3DLT9; P40027; Q3E844;
DT 02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 02-MAR-2010, sequence version 1.
DT 03-AUG-2022, entry version 57.
DE RecName: Full=Uncharacterized protein YER039C-A;
GN OrderedLocusNames=YER039C-A;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169868;
RA Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA Botstein D., Davis R.W.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL Nature 387:78-81(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- MISCELLANEOUS: Present with 98 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the TPT transporter family. SLC35D subfamily.
CC {ECO:0000305}.
CC -!- CAUTION: This is a truncated version of GDP-mannose transporter 2.
CC Strain S288c has a stop codon in position 73, which disrupts the gene
CC coding for this protein and produces two ORFs YER039C-A and YER039C. A
CC contiguous sequence for GDP-mannose transporter 2 can be found in
CC strain Lalvin EC1118 (AC C8Z742). {ECO:0000305}.
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DR EMBL; U18796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BK006939; DAA07693.1; -; Genomic_DNA.
DR RefSeq; NP_010957.1; NM_001184319.1.
DR AlphaFoldDB; P0CD97; -.
DR SMR; P0CD97; -.
DR BioGRID; 36775; 52.
DR STRING; 4932.YER039C-A; -.
DR PaxDb; P0CD97; -.
DR EnsemblFungi; YER039C-A_mRNA; YER039C-A; YER039C-A.
DR GeneID; 856762; -.
DR KEGG; sce:YER039C-A; -.
DR SGD; S000007226; YER039C-A.
DR VEuPathDB; FungiDB:YER039C-A; -.
DR eggNOG; KOG1444; Eukaryota.
DR HOGENOM; CLU_2723613_0_0_1; -.
DR BioCyc; YEAST:G3O-30384-MON; -.
DR PRO; PR:P0CD97; -.
DR Proteomes; UP000002311; Chromosome V.
DR RNAct; P0CD97; protein.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..72
FT /note="Uncharacterized protein YER039C-A"
FT /id="PRO_0000391664"
FT TOPO_DOM 1..12
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 13..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 33..46
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 47..69
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 70..72
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 72 AA; 7986 MW; 56E9F06C296FAC8C CRC64;
MSKHKHEWTE SVANSGPASI LSYCASSILM TVTNKFVVNL DNFNMNFVML FVQSLVCTVT
LCILRIVGVA NF