ID   YR224_MIMIV             Reviewed;         540 AA.
AC   Q5UQB7;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   23-FEB-2022, entry version 63.
DE   RecName: Full=Putative BTB/POZ domain-containing protein R224;
GN   OrderedLocusNames=MIMI_R224;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the mimivirus BTB/WD family. {ECO:0000305}.
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DR   EMBL; AY653733; AAV50497.1; -; Genomic_DNA.
DR   RefSeq; YP_003986720.1; NC_014649.1.
DR   GeneID; 9924831; -.
DR   KEGG; vg:9924831; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   Pfam; PF00651; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..540
FT                   /note="Putative BTB/POZ domain-containing protein R224"
FT                   /id="PRO_0000186230"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          16..88
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
SQ   SEQUENCE   540 AA;  62603 MW;  C98AC5BA6625F49D CRC64;
     MDHLNLCRYL TESILTDLEL TLIDENENTL VINVHKLILS INCQYFETLF SGQFIDSQKN
     NLKLLVPDIH VVRDIIYGFY KNPIKYKNYP DWLYELKKIV CQNFLCLETN IEILHNIIVP
     TNGFDKLLDT IDLIGYDSDT ISLLVGNMPD NYDLTKLPIE LIRQMFDVPM FNMIYVSDKD
     GTFKIGNGNI SFNITSNTLI NNGHFEFSSI HNKIIYHHVC DIYVYDLLNY TTNKFTNPIS
     HTIKSIVLTP DQEYIIYDSS PQIISKFDFI SMEIIESRFA PTGAVVNDIF SSTELGHFGK
     IEELQCCNPN LLIIGSNVLS FYNVNDMLLM NIIENNIIPN DLYGRIYSSS IKKGRIFVSL
     LNDIIFVLSS INMYFIKPDT YEYIKKIHCN NFYNHDYCAT NNDFWDICNI NQDVIAILVG
     NLLTIYNWKL DKTIIQIDIC HTECNGSYCK IDKIVYDSTT KLLFVDCSNS RSGKKIYSIL
     MDNIDLNIPI NNVDFSIFSK NKIMRYGNPK CISGIKKFKI IDNYKSKLYN NIEKYLKNNQ