ID   YR407_MIMIV             Reviewed;         356 AA.
AC   Q5UQK1;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Putative RNA methyltransferase R407;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MIMI_R407;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], AND SUBCELLULAR
RP   LOCATION.
RX   PubMed=16971431; DOI=10.1128/jvi.00940-06;
RA   Renesto P., Abergel C., Decloquement P., Moinier D., Azza S., Ogata H.,
RA   Fourquet P., Gorvel J.-P., Claverie J.-M., Raoult D.;
RT   "Mimivirus giant particles incorporate a large fraction of anonymous and
RT   unique gene products.";
RL   J. Virol. 80:11678-11685(2006).
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:16971431}.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RNA M5U methyltransferase family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01024}.
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DR   EMBL; AY653733; AAV50676.1; -; Genomic_DNA.
DR   RefSeq; YP_003986911.1; NC_014649.1.
DR   SMR; Q5UQK1; -.
DR   GeneID; 9925028; -.
DR   KEGG; vg:9925028; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR045850; TRM2_euk.
DR   InterPro; IPR010280; U5_MeTrfase_fam.
DR   PANTHER; PTHR45904; PTHR45904; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS51687; SAM_MT_RNA_M5U; 1.
PE   1: Evidence at protein level;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase; Virion.
FT   CHAIN           1..356
FT                   /note="Putative RNA methyltransferase R407"
FT                   /id="PRO_0000162062"
FT   ACT_SITE        316
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01024"
FT   BINDING         184
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01024"
SQ   SEQUENCE   356 AA;  41389 MW;  19EE93AF137D9F58 CRC64;
     MYSDIIRKQS DCYDSIKNFC TSESQLYPIK FYPQNEYYAN KFGLDLNNLT QIDNNTISQK
     VLLEIAKIWA NFIMDSEYPV FDRKTGKGFW NNVSFKKNND NQLMVKILVV GQWIDKINSD
     YFDQLIELVY NKCRIDTHCI YLQYSQNKSS PDKQENIQLF AGSNGIQENI LGINFWITPF
     TFSQANPNTC EMLYETLHQF INIDHDKRSI ICYGRNVGHI CLTLKSTKNV WAYNPCPVVD
     SDLKRTLTSN IISVNIQLFL DTKCELISDK LNLLDQYDKS NYLLIVSPGR NGLKNNVIQA
     IKQSRSIIKE FYYVSCYSKS LIRDLKNIEN CHIEKAQAID LFPSTEFCET IVKIVL