ID   YR431_MIMIV             Reviewed;         399 AA.
AC   Q5UQM4;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   02-DEC-2020, entry version 69.
DE   RecName: Full=Putative 3'-5' exonuclease R431;
DE            EC=3.1.11.-;
GN   OrderedLocusNames=MIMI_R431;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
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DR   EMBL; AY653733; AAV50700.1; -; Genomic_DNA.
DR   RefSeq; YP_003986935.1; NC_014649.1.
DR   SMR; Q5UQM4; -.
DR   GeneID; 9925052; -.
DR   KEGG; vg:9925052; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.30.1370.50; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR   InterPro; IPR001374; R3H_dom.
DR   InterPro; IPR036867; R3H_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF01612; DNA_pol_A_exo1; 1.
DR   Pfam; PF01424; R3H; 1.
DR   SMART; SM00474; 35EXOc; 1.
DR   SMART; SM00393; R3H; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   SUPFAM; SSF82708; SSF82708; 1.
DR   PROSITE; PS51061; R3H; 1.
PE   4: Predicted;
KW   Exonuclease; Hydrolase; Nuclease; Reference proteome.
FT   CHAIN           1..399
FT                   /note="Putative 3'-5' exonuclease R431"
FT                   /id="PRO_0000249419"
FT   DOMAIN          118..297
FT                   /note="3'-5' exonuclease"
FT   DOMAIN          335..399
FT                   /note="R3H"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00382"
SQ   SEQUENCE   399 AA;  46309 MW;  AEFF5AA488227851 CRC64;
     MEQEIISAVQ DIIDFINTRG PTKVFVIDSH FKNNRSITPV WTKNDLSLVA FIKKFPEYFI
     IGTDLIVSHK NIPIDFQTII QSWNLVEDDF ALTEKIVGKK LTMFEFPNNL DIIVTSDFQI
     VDNWIENNIY DLKQEIIGLD TETLISGKSE KISIIQLSTS KHNIIIQVNQ MNTLPQNLNK
     VFFDESIIKV GVAIDIDAKK LLQYFPTINQ IKKTLDLSDL FKQTNFTKHI SINPKESIGL
     KILAAHVLDL YIENKGDSEI KKSNWNNPVL TSDQVKYAIT DSYLSLMIYN ELQLMTNNLD
     VKNLLKNFCH IDESSVKKNS KNNLTRRELE QKEQERRLKS IESKIKKWLK EDDSLTFEFE
     SMNAFYRRHV HTFVEKIPEL SSETKGTDPN KYVIITRHC