ID   YR592_MIMIV             Reviewed;         841 AA.
AC   Q5UP58;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Putative helicase R592;
DE            EC=3.6.4.-;
GN   OrderedLocusNames=MIMI_R592;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
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DR   EMBL; AY653733; AAV50855.1; -; Genomic_DNA.
DR   RefSeq; YP_003987107.1; NC_014649.1.
DR   GeneID; 9925228; -.
DR   KEGG; vg:9925228; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000330; SNF2_N.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2-rel_dom; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   ATP-binding; Coiled coil; Helicase; Hydrolase; Metal-binding;
KW   Nucleotide-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..841
FT                   /note="Putative helicase R592"
FT                   /id="PRO_0000253914"
FT   DOMAIN          72..309
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          531..682
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT   ZN_FING         451..491
FT                   /note="RING-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          195..215
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          678..841
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          413..450
FT                   /evidence="ECO:0000255"
FT   MOTIF           266..269
FT                   /note="DEAD box"
FT   COMPBIAS        681..695
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        696..724
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        725..745
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        760..780
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        787..801
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        812..841
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         85..92
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   841 AA;  95723 MW;  CC0A42A841858B2A CRC64;
     MSFFELDENS PKVDQPHGLK KVKLKDHQLT SIAAMRELET QASIVIDKPE IGSKFHASVG
     YCISDIEEFK DSTFVIETNS AILADKVGAG KTYTTIGLIL KALVPKAHDR HITGTDNFSI
     KMISAKECEP VNLIVVPHNL INQWADFLDK SKLKYLKLNA ESDFNAFLDI DYITKVYPLT
     REQISCKPIK NKPKKLPVKT TKKGGSKTQN KAQNDQKIYE RKSLNMKKIR QALDTHNVFL
     LNVYRYKLFR QIFLTNKRKW ARVIIDEMDS SAVPSIFDEY GNFNWFLTAT PSAIFNRSCR
     RYVNKIFGQR QNLLNYFVVK NKEEYVDKSM ILPKPFVFMI NTMIQRVVAV FKDLIPQEVL
     QLINSGNMKE AITKLNCDVD TEENIIKILT GKINTELHNL ETELEYVNNL IPQDVDAHEN
     RKKNIMNNIA RCKTKLESIK EKINSIKDEC CFICTDPFEN PTIMNCCKSI FCLKCLLTTL
     KTVGSKCPYC RHAIKSNKDY QIISSGGTSN KKKKSEIVGK YKFNEMDKAD VLEQVLSYIS
     KNDENPKILI FSDYSQTFEK ITKNIAKANL QYAYLSGTPA HITNLITEFE NGITNILMLN
     SQNFGSGLNL QSANYLILYH RMLPELETQV IGRAQRFGRK NNLRVIFMVN DNENRDCRLD
     SKPINILSDS ELWMITNPTD LNEEPDEESD EGSDEDVEKS KDKKSSDKKS SDKKKSEKKS
     SDKKSSNKKN SKKKTYVKPK SSKKTSQKVK KTDSDNESEL SGLSDSDDLD DSDDLGILSD
     SSDSDDFGNL SDSDDLSDSD ESEIEIPKKS KKTSKSSKKN KIGGSNKTLK KKAPVRKLIK
     V