ID   YRBE_BACSU              Reviewed;         341 AA.
AC   O05389;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 2.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Uncharacterized oxidoreductase YrbE;
DE            EC=1.-.-.-;
GN   Name=yrbE; OrderedLocusNames=BSU27770;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Tosato V., Bolotin A., Bertani I., Valentino I., Bruschi C.V.;
RT   "A 17.8 kb segment in the spoVB-nadC region of the Bacillus subtilis 168
RT   chromosome: sequencing and ruv operon identification.";
RL   Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 252-341.
RC   STRAIN=168 / PY79;
RX   PubMed=9025289; DOI=10.1099/00221287-143-1-157;
RA   Gomez M., Cutting S.M.;
RT   "BofC encodes a putative forespore regulator of the Bacillus subtilis sigma
RT   K checkpoint.";
RL   Microbiology 143:157-170(1997).
CC   -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. {ECO:0000305}.
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DR   EMBL; Y15896; CAB75327.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB14737.1; -; Genomic_DNA.
DR   EMBL; X93081; CAA63619.1; -; Genomic_DNA.
DR   PIR; D69972; D69972.
DR   RefSeq; NP_390655.1; NC_000964.3.
DR   RefSeq; WP_004398990.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O05389; -.
DR   SMR; O05389; -.
DR   STRING; 224308.BSU27770; -.
DR   jPOST; O05389; -.
DR   PaxDb; O05389; -.
DR   PRIDE; O05389; -.
DR   EnsemblBacteria; CAB14737; CAB14737; BSU_27770.
DR   GeneID; 936523; -.
DR   KEGG; bsu:BSU27770; -.
DR   PATRIC; fig|224308.179.peg.3017; -.
DR   eggNOG; COG0673; Bacteria.
DR   InParanoid; O05389; -.
DR   OMA; QVHAVNI; -.
DR   PhylomeDB; O05389; -.
DR   BioCyc; BSUB:BSU27770-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR   GO; GO:0006740; P:NADPH regeneration; IBA:GO_Central.
DR   InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR030827; Myo_inos_IolG.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR04380; myo_inos_iolG; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..341
FT                   /note="Uncharacterized oxidoreductase YrbE"
FT                   /id="PRO_0000091784"
SQ   SEQUENCE   341 AA;  37788 MW;  E3023CD874F90C5F CRC64;
     MTKQIVTGII GAGRIGKLHV QNISRIPHMK IKAISDIQAS RIKSWADSHQ IEYITSDYRD
     LLHDPDIDAI FICSPTAVHA QMIKEAAEAK KHIFCEKPVS FSLDETSEAL AAVRKHGVTL
     QVGFNRRFDP HFKKIKTIVE NGEIGTPHLL KITSRDPEPP NIDYVRTSGG LFMDMSIHDF
     DMARYIMGSE VTEVYAKGAA LVNPSFAELG DIDTAVITLT FENGAMAVID NSRQAVYGYD
     QRVEVFGTKG SAAADNSRPT TVEVSTADFV MKDKPHFFFL ERYKDSYEEE ILRFAEAIGT
     NQETPCTGND GLQAGRIARA AQQSLAFGMP VSIEHTEKIA F