ID   YRC3_CAEEL              Reviewed;         496 AA.
AC   Q10042;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 3.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Probable G-protein coupled receptor K01A12.3;
GN   ORFNames=K01A12.3;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000305}.
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DR   EMBL; FO081128; CCD69326.1; -; Genomic_DNA.
DR   PIR; T16513; T16513.
DR   RefSeq; NP_509462.3; NM_077061.3.
DR   AlphaFoldDB; Q10042; -.
DR   SMR; Q10042; -.
DR   BioGRID; 51547; 2.
DR   STRING; 6239.K01A12.3; -.
DR   PaxDb; Q10042; -.
DR   EnsemblMetazoa; K01A12.3.1; K01A12.3.1; WBGene00019287.
DR   GeneID; 186832; -.
DR   KEGG; cel:CELE_K01A12.3; -.
DR   UCSC; K01A12.3; c. elegans.
DR   CTD; 186832; -.
DR   WormBase; K01A12.3; CE40086; WBGene00019287; -.
DR   eggNOG; ENOG502RETG; Eukaryota.
DR   HOGENOM; CLU_540032_0_0_1; -.
DR   InParanoid; Q10042; -.
DR   OMA; AYTIMAN; -.
DR   OrthoDB; 639335at2759; -.
DR   PRO; PR:Q10042; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00019287; Expressed in larva and 2 other tissues.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   PRINTS; PR00237; GPCRRHODOPSN.
PE   3: Inferred from homology;
KW   Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane;
KW   Receptor; Reference proteome; Transducer; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..496
FT                   /note="Probable G-protein coupled receptor K01A12.3"
FT                   /id="PRO_0000065391"
FT   TOPO_DOM        1..19
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        20..40
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        41..58
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..128
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        129..149
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        150..169
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        170..190
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        191..216
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        217..237
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        238..285
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        307..318
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        319..339
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        340..496
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          451..470
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        111
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   496 AA;  55855 MW;  103C3CC3E2BB6966 CRC64;
     MESVTRHRAD MISFFTFDSY ISIVGVAYTA VGLLGVFCNV TTVIMILTNR VFRLSAYTIM
     ANVALADSIV MLIAGVACGM DVMWPNPNDL TSFIPSLEEP YQKIAPVSLR NDSKTDSSAA
     GFETGNIHAV LSFSFVAAWT AGVISYAMLG TNRCIAICYY GTKARALNQV SVAVACSAST
     WIVGIAAALV GTLSQPMIGI QRTMWSISFL EPRPHTTLFF TLLCAANLLG LGAQWVCSTL
     VLLKIRQVKK KISKNKLNQN SANRFRKQVI LALNEIIVTG NFKARLTFQF FYPSILCTIS
     TFLFFIKPYA FEYLSGWQLV ILHLLWLCNH TCNPFIYAYF NDRMRLTYKE ILTCAAIRYQ
     IRKRRSSHPF RMHGRHNVSK RSNAAGMKST RISARSGRTN RDGNFVRNSL QMQSRDFEQL
     CEFIMRVNPL YDSSEGWRES SDDEPFQPEF TKELESAHNQ GGSSRFDSER EAKSIVLDLG
     RQTVEHWVKF AKKASI