ID   CBRC_ECOLI              Reviewed;         195 AA.
AC   P31469; Q2M835;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=UPF0167 protein CbrC;
DE   AltName: Full=CreB-regulated gene C protein;
GN   Name=cbrC; Synonyms=yieJ; OrderedLocusNames=b3717, JW3695;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=7686882; DOI=10.1006/geno.1993.1230;
RA   Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.;
RT   "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome:
RT   organizational symmetry around the origin of replication.";
RL   Genomics 16:551-561(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   INDUCTION BY CREBC.
RX   PubMed=11350954; DOI=10.1074/jbc.m011186200;
RA   Avison M.B., Horton R.E., Walsh T.R., Bennett P.M.;
RT   "Escherichia coli CreBC is a global regulator of gene expression that
RT   responds to growth in minimal media.";
RL   J. Biol. Chem. 276:26955-26961(2001).
RN   [5]
RP   MUTANT STUDIES.
RX   PubMed=12897016; DOI=10.1128/jb.185.16.4956-4972.2003;
RA   Zhou L., Lei X.-H., Bochner B.R., Wanner B.L.;
RT   "Phenotype microarray analysis of Escherichia coli K-12 mutants with
RT   deletions of all two-component systems.";
RL   J. Bacteriol. 185:4956-4972(2003).
CC   -!- INDUCTION: Induced by the two-component regulatory system CreC/CreB.
CC       {ECO:0000269|PubMed:11350954}.
CC   -!- MISCELLANEOUS: Disruption of this gene leads to hypersensibility to
CC       nitrofurazone.
CC   -!- SIMILARITY: Belongs to the UPF0167 family. {ECO:0000305}.
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DR   EMBL; L10328; AAA62068.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76740.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77571.1; -; Genomic_DNA.
DR   PIR; F65174; F65174.
DR   RefSeq; NP_418173.1; NC_000913.3.
DR   RefSeq; WP_000193072.1; NZ_LN832404.1.
DR   AlphaFoldDB; P31469; -.
DR   BioGRID; 4263198; 3.
DR   IntAct; P31469; 14.
DR   STRING; 511145.b3717; -.
DR   PaxDb; P31469; -.
DR   PRIDE; P31469; -.
DR   DNASU; 948230; -.
DR   EnsemblBacteria; AAC76740; AAC76740; b3717.
DR   EnsemblBacteria; BAE77571; BAE77571; BAE77571.
DR   GeneID; 948230; -.
DR   KEGG; ecj:JW3695; -.
DR   KEGG; eco:b3717; -.
DR   PATRIC; fig|511145.12.peg.3840; -.
DR   EchoBASE; EB1678; -.
DR   eggNOG; COG3196; Bacteria.
DR   HOGENOM; CLU_108448_0_0_6; -.
DR   InParanoid; P31469; -.
DR   OMA; YLCPWCI; -.
DR   PhylomeDB; P31469; -.
DR   BioCyc; EcoCyc:EG11727-MON; -.
DR   PRO; PR:P31469; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0030153; P:bacteriocin immunity; IMP:EcoCyc.
DR   InterPro; IPR005363; UPF0167.
DR   Pfam; PF03691; UPF0167; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..195
FT                   /note="UPF0167 protein CbrC"
FT                   /id="PRO_0000209365"
SQ   SEQUENCE   195 AA;  22485 MW;  84AFD84EBA99C563 CRC64;
     MTQNIRPLPQ FKYHPKPLET GAFEQDKTVE CDCCEQQTSV YYSGPFYCVD EVEHLCPWCI
     ADGSAAEKFA GSFQDDASIE GVEFEYDEED EFAGIKNTYP DEMLKELVER TPGYHGWQQE
     FWLAHCGDFC VFIGYVGWND IKDRLDEFAN LEEDCENFGI RNSDLAKCLQ KGGHCQGYLF
     RCLHCGKLRL WGDFS