ID   YRRT_BACSU              Reviewed;         213 AA.
AC   O32029;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Uncharacterized methyltransferase YrrT;
DE            EC=2.1.1.-;
GN   Name=yrrT; OrderedLocusNames=BSU27280;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   INDUCTION.
RX   PubMed=17056751; DOI=10.1128/jb.01273-06;
RA   Hullo M.-F., Auger S., Soutourina O., Barzu O., Yvon M., Danchin A.,
RA   Martin-Verstraete I.;
RT   "Conversion of methionine to cysteine in Bacillus subtilis and its
RT   regulation.";
RL   J. Bacteriol. 189:187-197(2007).
CC   -!- FUNCTION: Could be a S-adenosyl-L-methionine-dependent
CC       methyltransferase. {ECO:0000250}.
CC   -!- INDUCTION: By methionine. Repressed by sulfate and cysteine.
CC       {ECO:0000269|PubMed:17056751}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. YrrT family.
CC       {ECO:0000305}.
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DR   EMBL; AL009126; CAB14670.1; -; Genomic_DNA.
DR   PIR; C69980; C69980.
DR   RefSeq; NP_390606.1; NC_000964.3.
DR   RefSeq; WP_003229807.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O32029; -.
DR   SMR; O32029; -.
DR   STRING; 224308.BSU27280; -.
DR   PaxDb; O32029; -.
DR   PRIDE; O32029; -.
DR   EnsemblBacteria; CAB14670; CAB14670; BSU_27280.
DR   GeneID; 937566; -.
DR   KEGG; bsu:BSU27280; -.
DR   PATRIC; fig|224308.179.peg.2964; -.
DR   eggNOG; COG2226; Bacteria.
DR   InParanoid; O32029; -.
DR   OMA; FEDWAAT; -.
DR   PhylomeDB; O32029; -.
DR   BioCyc; BSUB:BSU27280-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IBA:GO_Central.
DR   GO; GO:0031167; P:rRNA methylation; IBA:GO_Central.
DR   Gene3D; 3.40.50.150; -; 1.
DR   HAMAP; MF_02100; Methyltr_YrrT; 1.
DR   InterPro; IPR001737; KsgA/Erm.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR020598; rRNA_Ade_methylase_Trfase_N.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR023553; Uncharacterised_MeTfrase_YrrT.
DR   PANTHER; PTHR11727; PTHR11727; 1.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   SMART; SM00650; rADc; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   2: Evidence at transcript level;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..213
FT                   /note="Uncharacterized methyltransferase YrrT"
FT                   /id="PRO_0000373848"
FT   BINDING         53
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         74
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         97
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   213 AA;  24196 MW;  F6107FA526B1B48F CRC64;
     MGREFIPLFE DWAATYDQTV QGLDIQYKEA FRGYDHILDA IVRKSGTHVL EFGPGTGNLT
     AKLLDAGKTV FGIEPSPAMR KLASDKLSGR TEIVDGDFLT FPEPPFQADT IVSSYAFHHL
     TDEEKRAAIK QYGKYLHLHD KIVFADTVFE NAQAYQQAID KARSQGFYQL ANDLETEHYP
     TLDALKEMFT AEGFAVRFTQ QNDFVWIMEA IKR