YS48_CAEEL
ID YS48_CAEEL Reviewed; 587 AA.
AC Q09374; Q95PX5;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Uncharacterized protein ZK177.8;
GN ORFNames=ZK177.8;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=a;
CC IsoId=Q09374-1; Sequence=Displayed;
CC Name=b;
CC IsoId=Q09374-2; Sequence=VSP_002452;
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DR EMBL; FO080583; CCD64860.1; -; Genomic_DNA.
DR EMBL; FO080583; CCD64861.1; -; Genomic_DNA.
DR PIR; T27765; T27765.
DR RefSeq; NP_495054.1; NM_062653.3. [Q09374-1]
DR RefSeq; NP_495055.1; NM_062654.3. [Q09374-2]
DR PDB; 6PWY; X-ray; 1.81 A; A/B/C/D=41-565.
DR PDBsum; 6PWY; -.
DR AlphaFoldDB; Q09374; -.
DR SMR; Q09374; -.
DR BioGRID; 39279; 1.
DR IntAct; Q09374; 1.
DR STRING; 6239.ZK177.8a; -.
DR EPD; Q09374; -.
DR PaxDb; Q09374; -.
DR PeptideAtlas; Q09374; -.
DR EnsemblMetazoa; ZK177.8a.1; ZK177.8a.1; WBGene00022673. [Q09374-1]
DR EnsemblMetazoa; ZK177.8a.2; ZK177.8a.2; WBGene00022673. [Q09374-1]
DR EnsemblMetazoa; ZK177.8b.1; ZK177.8b.1; WBGene00022673. [Q09374-2]
DR EnsemblMetazoa; ZK177.8b.2; ZK177.8b.2; WBGene00022673. [Q09374-2]
DR EnsemblMetazoa; ZK177.8b.3; ZK177.8b.3; WBGene00022673. [Q09374-2]
DR GeneID; 173937; -.
DR KEGG; cel:CELE_ZK177.8; -.
DR UCSC; ZK177.8a; c. elegans. [Q09374-1]
DR CTD; 173937; -.
DR WormBase; ZK177.8a; CE07618; WBGene00022673; -. [Q09374-1]
DR WormBase; ZK177.8b; CE02097; WBGene00022673; -. [Q09374-2]
DR eggNOG; KOG2681; Eukaryota.
DR GeneTree; ENSGT00390000013867; -.
DR InParanoid; Q09374; -.
DR OMA; NCEHSRF; -.
DR OrthoDB; 835545at2759; -.
DR PhylomeDB; Q09374; -.
DR Reactome; R-CEL-8956319; Nucleotide catabolism.
DR PRO; PR:Q09374; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00022673; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008832; F:dGTPase activity; IBA:GO_Central.
DR GO; GO:0006203; P:dGTP catabolic process; IBA:GO_Central.
DR CDD; cd00077; HDc; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR PROSITE; PS51831; HD; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Alternative splicing; Reference proteome.
FT CHAIN 1..587
FT /note="Uncharacterized protein ZK177.8"
FT /id="PRO_0000065507"
FT DOMAIN 92..262
FT /note="HD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
FT REGION 554..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..34
FT /note="Missing (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_002452"
FT STRAND 43..48
FT /evidence="ECO:0007829|PDB:6PWY"
FT TURN 49..51
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 52..56
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 60..64
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 67..70
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 71..74
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 79..83
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 92..113
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 115..117
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 121..133
FT /evidence="ECO:0007829|PDB:6PWY"
FT TURN 134..137
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 142..145
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 148..153
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 159..171
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 174..184
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 188..203
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 208..211
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 215..217
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 220..230
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 234..236
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 238..245
FT /evidence="ECO:0007829|PDB:6PWY"
FT TURN 250..252
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 256..269
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 277..284
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 286..291
FT /evidence="ECO:0007829|PDB:6PWY"
FT TURN 293..295
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 298..303
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 304..306
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 307..323
FT /evidence="ECO:0007829|PDB:6PWY"
FT TURN 324..326
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 328..344
FT /evidence="ECO:0007829|PDB:6PWY"
FT TURN 345..347
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 349..351
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 357..359
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 360..365
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 367..370
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 377..383
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 389..402
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 408..415
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 417..419
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 434..454
FT /evidence="ECO:0007829|PDB:6PWY"
FT TURN 458..463
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 466..473
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 475..477
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 483..486
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 510..515
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 522..529
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 531..535
FT /evidence="ECO:0007829|PDB:6PWY"
FT HELIX 537..553
FT /evidence="ECO:0007829|PDB:6PWY"
FT STRAND 561..563
FT /evidence="ECO:0007829|PDB:6PWY"
SQ SEQUENCE 587 AA; 66493 MW; 28603777C95880A8 CRC64;
MDSGQPWFPK IHTKEVRRRL SSLNIATPSS SPCNMNWQSL EPKHIINDNV YGTVKVPRPI
DKLIDTVEFQ RLRHLKQTGL VYLVYPNCEH SRFVHSLGTF SLAYALVDKL RHSQPSLNIT
ESDLICTSVA ALLHDVGHGP FSHLFDGEFA KRNGSRFKHE DMSILIIKKI MNKPEIKSEF
ACILGETDEE YAKSVTLITE LISGKPFDFQ DMDGFKDLPA DVREETVKNE WAIIGCGPEK
SFLFDVVSNS YNGHDVDKMD YLLRDSKASG VGITFSESTL ERLFNHVRVV IDPNSGLKRI
AYSIKCIGDL KAIGDSRQEL HSKVYQHKAV RFMETLMVDA LINAGDFLKY KGSNGELYSL
KNVTEDVDAF LKTTDYVEQE ILNSQITDPK MIEAQTALLK IQRREIGCKL GYFEMNPENA
TQLKGNCNNQ TGAAEVVKKV GQKMKEILEQ MDDTEEMDGK LKDIQFTVMH SVLGRGLDDK
THPIERQIFY DGKPSEHEGK QVVGFYPSED YVINNCPRMA TKWEIFVMGD RSLRKEPLLA
DRVKRALQLA GESEKFLTPR KRSPQDSPDE VSSSCSTAKR RLEFGSS
