ID   YSCB_YEREN              Reviewed;         137 AA.
AC   P0C2M8; Q01243; Q93KT2;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Chaperone protein YscB;
DE   AltName: Full=Yop proteins translocation protein B;
GN   Name=yscB;
OS   Yersinia enterocolitica.
OG   Plasmid pYV, Plasmid pYVe227, and Plasmid pYVa127/90.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=439-80 / Serotype O:9; PLASMID=pYV;
RX   PubMed=1860816; DOI=10.1128/jb.173.16.4994-5009.1991;
RA   Michiels T., Vanooteghem J.-C., de Rouvroit C., China B., Gustin A.,
RA   Boudry P., Cornelis G.R.;
RT   "Analysis of virC, an operon involved in the secretion of Yop proteins by
RT   Yersinia enterocolitica.";
RL   J. Bacteriol. 173:4994-5009(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=W22703 / Serotype O:9 / Biotype 2; PLASMID=pYVe227;
RA   Iriarte M., Lambermont I., Kerbourch C., Cornelis G.R.;
RT   "Detailed genetic map of the pYVe227 plasmid of Yersinia enterocolitica
RT   serotype O:9.";
RL   Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A127/90 / Serotype O:8 / Biotype 1B; PLASMID=pYVa127/90;
RX   PubMed=14527656; DOI=10.1016/s0923-2508(03)00147-5;
RA   Foultier B., Cornelis G.R.;
RT   "DNA sequence and analysis of the pYVa127/90 virulence plasmid of Yersinia
RT   enterocolitica strain A127/90.";
RL   Res. Microbiol. 154:553-557(2003).
RN   [4]
RP   FUNCTION, AND SUBUNIT.
RC   STRAIN=W22703 / Serotype O:9 / Biotype 2;
RX   PubMed=11514512; DOI=10.1128/jb.183.18.5293-5301.2001;
RA   Cheng L.W., Kay O., Schneewind O.;
RT   "Regulated secretion of YopN by the type III machinery of Yersinia
RT   enterocolitica.";
RL   J. Bacteriol. 183:5293-5301(2001).
CC   -!- FUNCTION: Functions as a specific chaperone for YopN. It could
CC       facilitate the secretion and the subsequent translocation of YopN.
CC       {ECO:0000269|PubMed:11514512}.
CC   -!- SUBUNIT: Interacts with SycN to form a complex which specifically binds
CC       to YopN. {ECO:0000269|PubMed:11514512}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell inner membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Not
CC       exported across the inner membrane. {ECO:0000250}.
CC   -!- INDUCTION: At 37 degrees Celsius in the absence of calcium.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M74011; AAC37019.1; -; Genomic_DNA.
DR   EMBL; AF102990; AAD16835.1; -; Genomic_DNA.
DR   EMBL; AY150843; AAN37552.1; -; Genomic_DNA.
DR   PIR; B40361; B40361.
DR   RefSeq; NP_052412.1; NC_002120.1.
DR   RefSeq; NP_783686.1; NC_004564.1.
DR   RefSeq; NP_863534.1; NC_005017.1.
DR   RefSeq; WP_005176453.1; NZ_NWMR01000033.1.
DR   RefSeq; WP_010891224.1; NZ_SJZK01000009.1.
DR   AlphaFoldDB; P0C2M8; -.
DR   SMR; P0C2M8; -.
DR   PATRIC; fig|630.129.peg.4373; -.
DR   OMA; SYHLRID; -.
DR   OrthoDB; 1914793at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR   InterPro; IPR013353; T3SS_YscB.
DR   InterPro; IPR010261; Tir_chaperone.
DR   Pfam; PF05932; CesT; 1.
DR   TIGRFAMs; TIGR02513; type_III_yscB; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Chaperone; Cytoplasm; Membrane;
KW   Plasmid.
FT   CHAIN           1..137
FT                   /note="Chaperone protein YscB"
FT                   /id="PRO_0000066477"
FT   VARIANT         15
FT                   /note="K -> E (in plasmid pYVa127/90)"
FT   VARIANT         37
FT                   /note="T -> A (in plasmid pYVa127/90)"
FT   VARIANT         120
FT                   /note="H -> Y (in plasmid pYVa127/90)"
SQ   SEQUENCE   137 AA;  15469 MW;  A43AB7D3532B3535 CRC64;
     MQNLLKNLAT SLGRKPFVAD KQGVYRLTID KHLVMLTPHG SELVLRTPID APMLREGNNV
     NVTLLRSLMQ QALAWAKRYP QTLVLDDCGQ LVLEARLRLQ ELDTHGLQEV INKQLALLEH
     LIPQLTPFSV ASRVGWN