YSCH_YERPE
ID YSCH_YERPE Reviewed; 165 AA.
AC P68590; Q00929;
DT 07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=Yop proteins translocation protein H;
DE AltName: Full=Low calcium response locus protein P;
GN Name=yscH; Synonyms=lcrP;
GN OrderedLocusNames=YPCD1.57, y5021, y0024, YP_pCD26;
OS Yersinia pestis.
OG Plasmid pCD1.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM5 / Biovar Mediaevalis;
RX PubMed=9746557; DOI=10.1128/iai.66.10.4611-4623.1998;
RA Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA Blattner F.R.;
RT "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT Yersinia pestis KIM5.";
RL Infect. Immun. 66:4611-4623(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM5 / Biovar Mediaevalis;
RX PubMed=9748454; DOI=10.1128/jb.180.19.5192-5202.1998;
RA Hu P., Elliott J., McCready P., Skowronski E., Garnes J., Kobayashi A.,
RA Brubaker R.R., Garcia E.;
RT "Structural organization of virulence-associated plasmids of Yersinia
RT pestis.";
RL J. Bacteriol. 180:5192-5202(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Belongs to an operon involved in the translocation of Yop
CC proteins across the bacterial membranes or in the specific control of
CC this function.
CC -!- INTERACTION:
CC P68590; Q15276: RABEP1; Xeno; NbExp=2; IntAct=EBI-2845098, EBI-447043;
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DR EMBL; AF074612; AAC69828.1; -; Genomic_DNA.
DR EMBL; AF053946; AAC62547.1; -; Genomic_DNA.
DR EMBL; AL117189; CAB54934.1; -; Genomic_DNA.
DR EMBL; AE017043; AAS58545.1; -; Genomic_DNA.
DR PIR; T43568; T43568.
DR RefSeq; NP_395191.1; NC_003131.1.
DR RefSeq; NP_857725.1; NC_004836.1.
DR RefSeq; NP_857920.1; NC_004839.1.
DR RefSeq; WP_002212915.1; NZ_WUCM01000070.1.
DR PDB; 1Z21; X-ray; 1.50 A; A=38-149.
DR PDBsum; 1Z21; -.
DR AlphaFoldDB; P68590; -.
DR SMR; P68590; -.
DR IntAct; P68590; 7.
DR MINT; P68590; -.
DR STRING; 214092.5832477; -.
DR DNASU; 1149284; -.
DR EnsemblBacteria; AAS58545; AAS58545; YP_pCD26.
DR KEGG; ype:YPCD1.57; -.
DR KEGG; ypm:YP_pCD26; -.
DR PATRIC; fig|214092.21.peg.67; -.
DR eggNOG; ENOG5033585; Bacteria.
DR HOGENOM; CLU_1610154_0_0_6; -.
DR OMA; LIPRNGM; -.
DR EvolutionaryTrace; P68590; -.
DR Proteomes; UP000000815; Plasmid pCD1.
DR Proteomes; UP000001019; Plasmid pCD1.
DR GO; GO:0030257; C:type III protein secretion system complex; IEA:InterPro.
DR GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR Gene3D; 1.10.10.1000; -; 1.
DR InterPro; IPR013349; T3SS_YopR.
DR InterPro; IPR041814; YopR_core.
DR Pfam; PF09025; T3SS_needle_reg; 1.
DR TIGRFAMs; TIGR02509; type_III_yopR; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Plasmid; Reference proteome; Virulence.
FT CHAIN 1..165
FT /note="Yop proteins translocation protein H"
FT /id="PRO_0000066484"
FT HELIX 43..56
FT /evidence="ECO:0007829|PDB:1Z21"
FT HELIX 62..80
FT /evidence="ECO:0007829|PDB:1Z21"
FT HELIX 89..103
FT /evidence="ECO:0007829|PDB:1Z21"
FT HELIX 108..119
FT /evidence="ECO:0007829|PDB:1Z21"
FT HELIX 131..144
FT /evidence="ECO:0007829|PDB:1Z21"
SQ SEQUENCE 165 AA; 18348 MW; B0DCD99C52B95905 CRC64;
MTVTLNRGSI TSLMSSSQAV STLQPVASEL KTQLENKLKS ESAEKTREVL WQQYYASNPP
DHAVLEVLAT PVREALLARF GQHQGSVVPA IDLPELRSVL QQFDSFGKRW EAILLQVLEG
IKPNESQVGL PYLSELINKE LMILLPSNSI VDSLLHNSHQ IDMDT
