YSCI_YERPE
ID YSCI_YERPE Reviewed; 115 AA.
AC P69970; Q00933; Q663I1;
DT 04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Yop proteins translocation protein I;
DE AltName: Full=Low calcium response locus protein O;
GN Name=yscI; Synonyms=lcrO;
GN OrderedLocusNames=YPCD1.58, y5020, y0023, YP_pCD25;
OS Yersinia pestis.
OG Plasmid pCD1.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM5 / Biovar Mediaevalis;
RX PubMed=9746557; DOI=10.1128/iai.66.10.4611-4623.1998;
RA Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA Blattner F.R.;
RT "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT Yersinia pestis KIM5.";
RL Infect. Immun. 66:4611-4623(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM5 / Biovar Mediaevalis;
RX PubMed=9748454; DOI=10.1128/jb.180.19.5192-5202.1998;
RA Hu P., Elliott J., McCready P., Skowronski E., Garnes J., Kobayashi A.,
RA Brubaker R.R., Garcia E.;
RT "Structural organization of virulence-associated plasmids of Yersinia
RT pestis.";
RL J. Bacteriol. 180:5192-5202(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Belongs to an operon involved in the translocation of Yop
CC proteins across the bacterial membranes or in the specific control of
CC this function. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the YscI/HrpB family. {ECO:0000305}.
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DR EMBL; AF074612; AAC69776.1; -; Genomic_DNA.
DR EMBL; AF053946; AAC62608.1; -; Genomic_DNA.
DR EMBL; AL117189; CAB54935.1; -; Genomic_DNA.
DR EMBL; AE017043; AAS58544.1; -; Genomic_DNA.
DR PIR; T43567; T43567.
DR RefSeq; NP_395192.1; NC_003131.1.
DR RefSeq; NP_857724.1; NC_004836.1.
DR RefSeq; NP_857919.1; NC_004839.1.
DR RefSeq; WP_002212914.1; NZ_WUCM01000070.1.
DR AlphaFoldDB; P69970; -.
DR SMR; P69970; -.
DR IntAct; P69970; 2.
DR MINT; P69970; -.
DR STRING; 214092.5832478; -.
DR EnsemblBacteria; AAS58544; AAS58544; YP_pCD25.
DR GeneID; 66841090; -.
DR KEGG; ype:YPCD1.58; -.
DR KEGG; ypm:YP_pCD25; -.
DR PATRIC; fig|214092.21.peg.68; -.
DR eggNOG; ENOG50336BE; Bacteria.
DR HOGENOM; CLU_171571_0_0_6; -.
DR OMA; NTQYTEV; -.
DR Proteomes; UP000000815; Plasmid pCD1.
DR Proteomes; UP000001019; Plasmid pCD1.
DR GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR InterPro; IPR012670; T3SS_YscI/HrpB.
DR Pfam; PF17001; T3SS_basalb_I; 1.
DR TIGRFAMs; TIGR02497; yscI_hrpB_dom; 1.
PE 3: Inferred from homology;
KW Plasmid; Reference proteome; Virulence.
FT CHAIN 1..115
FT /note="Yop proteins translocation protein I"
FT /id="PRO_0000066487"
SQ SEQUENCE 115 AA; 12669 MW; 441C329F173E19AB CRC64;
MPNIEIAQAD EVIITTLEEL GPAEPTTDQI MRFDAAMSED TQGLGHSLLK EVSDIQKSFK
TVKSDLHTKL AVSVDNPNDL MLMQWSLIRI TIQEELIAKT AGRMSQNVET LSKGG