ID   YSCJ_YERPE              Reviewed;         244 AA.
AC   P69972; Q00926; Q663I0;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Yop proteins translocation lipoprotein J;
DE   AltName: Full=Lipoprotein YlpB;
DE   AltName: Full=Low calcium response locus protein KA;
DE   Flags: Precursor;
GN   Name=yscJ; Synonyms=lcrKA, ylpB;
GN   OrderedLocusNames=YPCD1.59, y5019, y0022, YP_pCD24;
OS   Yersinia pestis.
OG   Plasmid pCD1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM5 / Biovar Mediaevalis;
RX   PubMed=9746557; DOI=10.1128/iai.66.10.4611-4623.1998;
RA   Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA   Blattner F.R.;
RT   "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT   Yersinia pestis KIM5.";
RL   Infect. Immun. 66:4611-4623(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM5 / Biovar Mediaevalis;
RX   PubMed=9748454; DOI=10.1128/jb.180.19.5192-5202.1998;
RA   Hu P., Elliott J., McCready P., Skowronski E., Garnes J., Kobayashi A.,
RA   Brubaker R.R., Garcia E.;
RT   "Structural organization of virulence-associated plasmids of Yersinia
RT   pestis.";
RL   J. Bacteriol. 180:5192-5202(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: Required for the export process of the Yop proteins.
CC       {ECO:0000250}.
CC   -!- INTERACTION:
CC       P69972; Q56975: yscD; NbExp=2; IntAct=EBI-2860400, EBI-6413916;
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the YscJ lipoprotein family. {ECO:0000305}.
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DR   EMBL; AF074612; AAC69775.1; -; Genomic_DNA.
DR   EMBL; AF053946; AAC62607.1; -; Genomic_DNA.
DR   EMBL; AL117189; CAB54936.1; -; Genomic_DNA.
DR   EMBL; AE017043; AAS58543.1; -; Genomic_DNA.
DR   PIR; T43566; T43566.
DR   RefSeq; NP_395193.1; NC_003131.1.
DR   RefSeq; NP_857723.1; NC_004836.1.
DR   RefSeq; NP_857918.1; NC_004839.1.
DR   RefSeq; WP_002212912.1; NZ_WHLN01000049.1.
DR   AlphaFoldDB; P69972; -.
DR   SMR; P69972; -.
DR   IntAct; P69972; 2.
DR   STRING; 214092.5832479; -.
DR   DNASU; 1149282; -.
DR   EnsemblBacteria; AAS58543; AAS58543; YP_pCD24.
DR   GeneID; 66841089; -.
DR   KEGG; ype:YPCD1.59; -.
DR   KEGG; ypm:YP_pCD24; -.
DR   PATRIC; fig|214092.21.peg.69; -.
DR   eggNOG; COG4669; Bacteria.
DR   HOGENOM; CLU_073268_0_2_6; -.
DR   OMA; GRIQQMV; -.
DR   Proteomes; UP000000815; Plasmid pCD1.
DR   Proteomes; UP000001019; Plasmid pCD1.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 3.30.300.30; -; 1.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR006182; FliF_N_dom.
DR   InterPro; IPR003282; T3SS_HrcJ/YscJ.
DR   InterPro; IPR043427; YscJ/FliF.
DR   PANTHER; PTHR30046; PTHR30046; 1.
DR   Pfam; PF01514; YscJ_FliF; 1.
DR   PRINTS; PR01338; TYPE3OMKPROT.
DR   TIGRFAMs; TIGR02544; III_secr_YscJ; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Plasmid;
KW   Protein transport; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix; Transport; Virulence.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000305"
FT   CHAIN           19..244
FT                   /note="Yop proteins translocation lipoprotein J"
FT                   /id="PRO_0000018231"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   LIPID           19
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           19
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   244 AA;  27042 MW;  8DDA9E712938D8BC CRC64;
     MKVKTSLSTL ILILFLTGCK VDLYTGISQK EGNEMLALLR QEGLSADKEP DKDGKIKLLV
     EESDVAQAID ILKRKGYPHE SFSTLQDVFP KDGLISSPIE ELARLNYAKA QEISRTLSEI
     DGVLVARVHV VLPEEQNNKG KKGVAASASV FIKHAADIQF DTYIPQIKQL VNNSIEGLAY
     DRISVILVPS VDVRQSSHLP RNTSILSIQV SEESKGHLIG LLSLLILLLP VTNLAQYFWL
     QRKK