YSCK_YERPE
ID YSCK_YERPE Reviewed; 209 AA.
AC P69974; Q00927; Q663H9;
DT 04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Yop proteins translocation protein K;
DE AltName: Full=Low calcium response locus protein KB;
GN Name=yscK; Synonyms=lcrKB;
GN OrderedLocusNames=YPCD1.60, y5018, y0021, YP_pCD23;
OS Yersinia pestis.
OG Plasmid pCD1.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM5 / Biovar Mediaevalis;
RX PubMed=9746557; DOI=10.1128/iai.66.10.4611-4623.1998;
RA Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA Blattner F.R.;
RT "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT Yersinia pestis KIM5.";
RL Infect. Immun. 66:4611-4623(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM5 / Biovar Mediaevalis;
RX PubMed=9748454; DOI=10.1128/jb.180.19.5192-5202.1998;
RA Hu P., Elliott J., McCready P., Skowronski E., Garnes J., Kobayashi A.,
RA Brubaker R.R., Garcia E.;
RT "Structural organization of virulence-associated plasmids of Yersinia
RT pestis.";
RL J. Bacteriol. 180:5192-5202(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Belongs to an operon involved in the translocation of Yop
CC proteins across the bacterial membranes or in the specific control of
CC this function. {ECO:0000250}.
CC -!- INTERACTION:
CC P69974; O15162: PLSCR1; Xeno; NbExp=2; IntAct=EBI-2842860, EBI-740019;
CC P69974; Q13077: TRAF1; Xeno; NbExp=2; IntAct=EBI-2842860, EBI-359224;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAS58542.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AF074612; AAC69774.1; -; Genomic_DNA.
DR EMBL; AF053946; AAC62605.1; -; Genomic_DNA.
DR EMBL; AL117189; CAB54937.1; -; Genomic_DNA.
DR EMBL; AE017043; AAS58542.1; ALT_INIT; Genomic_DNA.
DR PIR; T43565; T43565.
DR RefSeq; NP_395194.1; NC_003131.1.
DR RefSeq; NP_857722.1; NC_004836.1.
DR RefSeq; NP_857917.1; NC_004839.1.
DR RefSeq; WP_002361471.1; NZ_WUCM01000070.1.
DR AlphaFoldDB; P69974; -.
DR SMR; P69974; -.
DR IntAct; P69974; 13.
DR MINT; P69974; -.
DR STRING; 214092.5832480; -.
DR DNASU; 1149281; -.
DR EnsemblBacteria; AAS58542; AAS58542; YP_pCD23.
DR GeneID; 66841088; -.
DR KEGG; ype:YPCD1.60; -.
DR KEGG; ypm:YP_pCD23; -.
DR PATRIC; fig|214092.21.peg.70; -.
DR eggNOG; ENOG5032ECP; Bacteria.
DR HOGENOM; CLU_108968_0_0_6; -.
DR OMA; VIPQWFH; -.
DR Proteomes; UP000000815; Plasmid pCD1.
DR Proteomes; UP000001019; Plasmid pCD1.
DR InterPro; IPR009510; T3SS_K.
DR Pfam; PF06578; YscK; 1.
PE 1: Evidence at protein level;
KW Plasmid; Reference proteome; Virulence.
FT CHAIN 1..209
FT /note="Yop proteins translocation protein K"
FT /id="PRO_0000066490"
SQ SEQUENCE 209 AA; 23991 MW; 1E19276045508988 CRC64;
MMENYITSFQ LRFCPAAYLH LEQLPSLWRS ILPYLPQWRD SAHLNAALLD EFSLDTDYEE
PHGLGALPLQ PQSQLELLLC RLGLVLHGEA IRRCVLASPL QQLLTLVNQE TLRQIIVQHE
LLIGPWPTHW QRPLPTEIES RTMIQSGLAF WLAAMEPQPQ AWCKRLSLRL PLATPSEPWL
VAESQRPLAQ TLCHKLVKQV TPTCSHLFK