YSCP_YERPE
ID YSCP_YERPE Reviewed; 455 AA.
AC P68587; P40295;
DT 07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Yop proteins translocation protein P;
GN Name=yscP; OrderedLocusNames=YPCD1.42, y5036, y0039, YP_pCD41;
OS Yersinia pestis.
OG Plasmid pCD1.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM5 / Biovar Mediaevalis;
RA Payne P.L., Fields K.A., Straley S.C.;
RL Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM5 / Biovar Mediaevalis;
RX PubMed=9746557; DOI=10.1128/iai.66.10.4611-4623.1998;
RA Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA Blattner F.R.;
RT "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT Yersinia pestis KIM5.";
RL Infect. Immun. 66:4611-4623(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KIM5 / Biovar Mediaevalis;
RX PubMed=9748454; DOI=10.1128/jb.180.19.5192-5202.1998;
RA Hu P., Elliott J., McCready P., Skowronski E., Garnes J., Kobayashi A.,
RA Brubaker R.R., Garcia E.;
RT "Structural organization of virulence-associated plasmids of Yersinia
RT pestis.";
RL J. Bacteriol. 180:5192-5202(1998).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Component of the yop secretion machinery. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SpaN family. {ECO:0000305}.
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DR EMBL; AF020214; AAB72199.1; -; Genomic_DNA.
DR EMBL; AF074612; AAC69789.1; -; Genomic_DNA.
DR EMBL; AF053946; AAC62562.1; -; Genomic_DNA.
DR EMBL; AL117189; CAB54919.1; -; Genomic_DNA.
DR EMBL; AE017043; AAS58560.1; -; Genomic_DNA.
DR PIR; T43583; T43583.
DR RefSeq; NP_395176.1; NC_003131.1.
DR RefSeq; NP_857740.1; NC_004836.1.
DR RefSeq; NP_857935.1; NC_004839.1.
DR RefSeq; WP_002212950.1; NZ_WUCM01000070.1.
DR AlphaFoldDB; P68587; -.
DR SMR; P68587; -.
DR IntAct; P68587; 22.
DR STRING; 214092.5832462; -.
DR DNASU; 1149299; -.
DR EnsemblBacteria; AAS58560; AAS58560; YP_pCD41.
DR KEGG; ype:YPCD1.42; -.
DR KEGG; ypm:YP_pCD41; -.
DR PATRIC; fig|214092.21.peg.53; -.
DR eggNOG; ENOG5032YMB; Bacteria.
DR HOGENOM; CLU_604021_0_0_6; -.
DR OMA; RHPKEEP; -.
DR Proteomes; UP000000815; Plasmid pCD1.
DR Proteomes; UP000001019; Plasmid pCD1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 3.30.750.140; -; 1.
DR InterPro; IPR021136; Flagellar_hook_control-like_C.
DR InterPro; IPR038610; FliK-like_C_sf.
DR InterPro; IPR013354; T3SS_YscP_C.
DR Pfam; PF02120; Flg_hook; 1.
DR TIGRFAMs; TIGR02514; type_III_yscP; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Plasmid; Reference proteome; Virulence.
FT CHAIN 1..455
FT /note="Yop proteins translocation protein P"
FT /id="PRO_0000180941"
FT REGION 38..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..455
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 455 AA; 50419 MW; F0D2FD09FDB61444 CRC64;
MNKITTRSPL EPEYQPLGKP HHALQACVDF EQALLHNNKG NCHPKEESLK PVRPHDLGKK
EGQKGDGLRA HAPLAATSQP GRKEVGLKPQ HNHQNNHDFN LSPLAEGATN RAHLYQQDSR
FDDRVESIIN ALMPLAPFLE GVTCETGTSS ESPCEPSGHD ELFVQQSPID SAQPVQLNSK
PTVQPLNPAA DGAEVIVWSV GRETPASIAK NQRDSRQKRL AEEPLALHQK ALPEICPPAV
SATPDDHLVA RWCATPVTEV AEKSARFPYK ATVQSEQLDM TELADRSQHL TDGVDSSKDT
IEPPRPEKLL LPREETLPEM YSLSFTAPVV TPGDHLLATM RATRLASVSE QLIQLAQRLA
VELELRGGSS QVTQLHLNLP ELGAIMVRIA EIPGKLHVEL IASREALRIL AQGSYDLLER
LQRIEPTQLD FQASDDSEQE SRQKRHVYEE WEAEE