ID   YSCT_YERPE              Reviewed;         261 AA.
AC   P69984; P40299; Q663J3;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Yop proteins translocation protein T;
GN   Name=yscT; OrderedLocusNames=YPCD1.46, y5032, y0035, YP_pCD37;
OS   Yersinia pestis.
OG   Plasmid pCD1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM5 / Biovar Mediaevalis;
RX   PubMed=9746557; DOI=10.1128/iai.66.10.4611-4623.1998;
RA   Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA   Blattner F.R.;
RT   "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT   Yersinia pestis KIM5.";
RL   Infect. Immun. 66:4611-4623(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM5 / Biovar Mediaevalis;
RX   PubMed=9748454; DOI=10.1128/jb.180.19.5192-5202.1998;
RA   Hu P., Elliott J., McCready P., Skowronski E., Garnes J., Kobayashi A.,
RA   Brubaker R.R., Garcia E.;
RT   "Structural organization of virulence-associated plasmids of Yersinia
RT   pestis.";
RL   J. Bacteriol. 180:5192-5202(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: Component of the yop secretion machinery. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family. {ECO:0000305}.
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DR   EMBL; AF074612; AAC69785.1; -; Genomic_DNA.
DR   EMBL; AF053946; AAC62558.1; -; Genomic_DNA.
DR   EMBL; AL117189; CAB54923.1; -; Genomic_DNA.
DR   EMBL; AE017043; AAS58556.1; -; Genomic_DNA.
DR   PIR; T43579; T43579.
DR   RefSeq; NP_395180.1; NC_003131.1.
DR   RefSeq; NP_857736.1; NC_004836.1.
DR   RefSeq; NP_857931.1; NC_004839.1.
DR   RefSeq; WP_002212938.1; NZ_WUCM01000070.1.
DR   AlphaFoldDB; P69984; -.
DR   SMR; P69984; -.
DR   IntAct; P69984; 1.
DR   STRING; 214092.5832466; -.
DR   DNASU; 1149295; -.
DR   EnsemblBacteria; AAS58556; AAS58556; YP_pCD37.
DR   GeneID; 66841102; -.
DR   KEGG; ype:YPCD1.46; -.
DR   KEGG; ypm:YP_pCD37; -.
DR   PATRIC; fig|214092.21.peg.57; -.
DR   eggNOG; COG4791; Bacteria.
DR   HOGENOM; CLU_063626_0_2_6; -.
DR   OMA; PFWLFES; -.
DR   Proteomes; UP000000815; Plasmid pCD1.
DR   Proteomes; UP000001019; Plasmid pCD1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR   InterPro; IPR002010; T3SS_IM_R.
DR   InterPro; IPR006304; T3SS_SpaR/YscT.
DR   PANTHER; PTHR30065; PTHR30065; 1.
DR   Pfam; PF01311; Bac_export_1; 1.
DR   PRINTS; PR00953; TYPE3IMRPROT.
DR   TIGRFAMs; TIGR01401; fliR_like_III; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Plasmid; Protein transport; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Virulence.
FT   CHAIN           1..261
FT                   /note="Yop proteins translocation protein T"
FT                   /id="PRO_0000192063"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   261 AA;  28451 MW;  1EE38E9EE07AD1F3 CRC64;
     MIADLIQRPL LTYTLLLPRF MACFVILPVL SKQLLGGVLL RNGIVCSLAL YVYPAVANQP
     YIEVDAFTLM LLIGKEIILG LLIGFVATIP FWALESAGFI VDNQRGAAMA SLLNPGLDSQ
     TSPTGLLLTQ TLITIFFSGG AFLSLLSALF HSYVNWPVAS FFPAVSEQWV DFFYNQFSQI
     LLIAAVLAAP LLIAMFLAEF GLALISRFAP SLNVFVLAMP IKSAIASLLL VIYCMQMMSH
     ASKAMLLVMD PISLLIPVLE K