ID   YSCX_YEREN              Reviewed;         122 AA.
AC   P0C2N4; O68696; P21208;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Yop proteins translocation protein X;
GN   Name=yscX;
OS   Yersinia enterocolitica.
OG   Plasmid pYV, Plasmid pYVe227, and Plasmid pYVa127/90.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION.
RC   STRAIN=Serotype O:3; PLASMID=pYV;
RX   PubMed=2160939; DOI=10.1128/jb.172.6.3152-3162.1990;
RA   Viitanen A.-M., Toivanen P., Skurnik M.;
RT   "The lcrE gene is part of an operon in the lcr region of Yersinia
RT   enterocolitica O:3.";
RL   J. Bacteriol. 172:3152-3162(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=W22703 / Serotype O:9 / Biotype 2; PLASMID=pYVe227;
RA   Iriarte M., Lambermont I., Kerbourch C., Cornelis G.R.;
RT   "Detailed genetic map of the pYVe227 plasmid of Yersinia enterocolitica
RT   serotype O:9.";
RL   Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A127/90 / Serotype O:8 / Biotype 1B; PLASMID=pYVa127/90;
RX   PubMed=14527656; DOI=10.1016/s0923-2508(03)00147-5;
RA   Foultier B., Cornelis G.R.;
RT   "DNA sequence and analysis of the pYVa127/90 virulence plasmid of Yersinia
RT   enterocolitica strain A127/90.";
RL   Res. Microbiol. 154:553-557(2003).
RN   [4]
RP   FUNCTION.
RC   PLASMID=pYV;
RX   PubMed=9882687; DOI=10.1128/jb.181.2.675-680.1999;
RA   Iriarte M., Cornelis G.R.;
RT   "Identification of SycN, YscX, and YscY, three new elements of the Yersinia
RT   Yop virulon.";
RL   J. Bacteriol. 181:675-680(1999).
CC   -!- FUNCTION: Required for Yop secretion. {ECO:0000269|PubMed:9882687}.
CC   -!- SUBUNIT: Interacts with YscY. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted. Note=Secreted via the type III
CC       secretion system. {ECO:0000250}.
CC   -!- INDUCTION: Temperature seems to play the major role in regulation of
CC       transcription of the lcrE-containing operon of pYV, whereas Ca(2+)
CC       concentration has only a moderate effect at 37 degrees Celsius, and no
CC       effect at room temperature. {ECO:0000269|PubMed:2160939}.
CC   -!- DOMAIN: The region between residues 50 and 110, which contains the
CC       predicted coiled coil domain, is essential for interaction with YscY.
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: May possess both an mRNA signal and a syc-dependent
CC       signal capable of directing its export through the type III secretion
CC       system. {ECO:0000250}.
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DR   EMBL; M32097; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AF102990; AAD16820.1; -; Genomic_DNA.
DR   EMBL; AY150843; AAN37521.1; -; Genomic_DNA.
DR   PIR; D35392; D35392.
DR   RefSeq; NP_052397.1; NC_002120.1.
DR   RefSeq; NP_783670.1; NC_004564.1.
DR   RefSeq; NP_863519.1; NC_005017.1.
DR   RefSeq; WP_010891214.1; NZ_SJZK01000009.1.
DR   AlphaFoldDB; P0C2N4; -.
DR   PATRIC; fig|630.129.peg.4358; -.
DR   OMA; KYRQQFD; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR012672; T3SS_YscX.
DR   Pfam; PF09474; Type_III_YscX; 1.
DR   TIGRFAMs; TIGR02502; type_III_YscX; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Plasmid; Secreted.
FT   CHAIN           1..122
FT                   /note="Yop proteins translocation protein X"
FT                   /id="PRO_0000066499"
FT   COILED          71..87
FT                   /evidence="ECO:0000255"
FT   VARIANT         29
FT                   /note="D -> E (in plasmid pYVa127/90)"
SQ   SEQUENCE   122 AA;  13742 MW;  050F5E2D6909BB00 CRC64;
     MSRIITAPHI GIEKLSAISL EELSCGLPDR YALPPDGHPV EPHLERLYPT AQSKRSLWDF
     ASPGYTFHGL HRAQDYRREL DTLQSLLTTS QSSELQAAAA LLKCQQDDDR LLQIILNLLH
     KV