ID   YSCX_YERPE              Reviewed;         122 AA.
AC   P61416; O68696;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2004, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Yop proteins translocation protein X;
GN   Name=yscX; OrderedLocusNames=YPCD1.36c, y5042, y0045, YP_pCD47;
OS   Yersinia pestis.
OG   Plasmid pCD1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM5 / Biovar Mediaevalis;
RX   PubMed=9746557; DOI=10.1128/iai.66.10.4611-4623.1998;
RA   Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA   Blattner F.R.;
RT   "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT   Yersinia pestis KIM5.";
RL   Infect. Immun. 66:4611-4623(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM5 / Biovar Mediaevalis;
RX   PubMed=9748454; DOI=10.1128/jb.180.19.5192-5202.1998;
RA   Hu P., Elliott J., McCready P., Skowronski E., Garnes J., Kobayashi A.,
RA   Brubaker R.R., Garcia E.;
RT   "Structural organization of virulence-associated plasmids of Yersinia
RT   pestis.";
RL   J. Bacteriol. 180:5192-5202(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
RN   [5]
RP   CHARACTERIZATION.
RC   STRAIN=KIM8;
RX   PubMed=10714987; DOI=10.1128/jb.182.7.1834-1843.2000;
RA   Day J.B., Plano G.V.;
RT   "The Yersinia pestis YscY protein directly binds YscX, a secreted component
RT   of the type III secretion machinery.";
RL   J. Bacteriol. 182:1834-1843(2000).
CC   -!- FUNCTION: Required for Yop secretion.
CC   -!- SUBUNIT: Interacts with YscY.
CC   -!- SUBCELLULAR LOCATION: Secreted. Note=Secreted via the type III
CC       secretion system.
CC   -!- DOMAIN: The region between residues 50 and 110, which contains the
CC       predicted coiled coil domain, is essential for interaction with YscY.
CC   -!- MISCELLANEOUS: May possess both an mRNA signal and a syc-dependent
CC       signal capable of directing its export through the type III secretion
CC       system.
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DR   EMBL; AF074612; AAC69795.1; -; Genomic_DNA.
DR   EMBL; AF053946; AAC62569.1; -; Genomic_DNA.
DR   EMBL; AL117189; CAB54913.1; -; Genomic_DNA.
DR   EMBL; AE017043; AAS58566.1; -; Genomic_DNA.
DR   PIR; T43589; T43589.
DR   RefSeq; NP_395170.1; NC_003131.1.
DR   RefSeq; NP_857746.1; NC_004836.1.
DR   RefSeq; NP_857941.1; NC_004839.1.
DR   RefSeq; WP_002212969.1; NZ_WHLN01000049.1.
DR   AlphaFoldDB; P61416; -.
DR   IntAct; P61416; 12.
DR   MINT; P61416; -.
DR   STRING; 214092.5832456; -.
DR   EnsemblBacteria; AAS58566; AAS58566; YP_pCD47.
DR   GeneID; 66841112; -.
DR   KEGG; ype:YPCD1.36c; -.
DR   KEGG; ypm:YP_pCD47; -.
DR   PATRIC; fig|214092.21.peg.47; -.
DR   eggNOG; ENOG5032YR9; Bacteria.
DR   HOGENOM; CLU_2033138_0_0_6; -.
DR   OMA; KYRQQFD; -.
DR   Proteomes; UP000000815; Plasmid pCD1.
DR   Proteomes; UP000001019; Plasmid pCD1.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR012672; T3SS_YscX.
DR   Pfam; PF09474; Type_III_YscX; 1.
DR   TIGRFAMs; TIGR02502; type_III_YscX; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Plasmid; Reference proteome; Secreted.
FT   CHAIN           1..122
FT                   /note="Yop proteins translocation protein X"
FT                   /id="PRO_0000066500"
FT   COILED          71..87
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   122 AA;  13756 MW;  1E15EF87D908AA01 CRC64;
     MSRIITAPHI GIEKLSAISL EELSCGLPER YALPPDGHPV EPHLERLYPT AQSKRSLWDF
     ASPGYTFHGL HRAQDYRREL DTLQSLLTTS QSSELQAAAA LLKCQQDDDR LLQIILNLLH
     KV