ID   YSCY_YERPE              Reviewed;         114 AA.
AC   P61417; P21209;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2004, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Chaperone protein YscY;
DE   AltName: Full=Yop proteins translocation protein Y;
GN   Name=yscY; OrderedLocusNames=YPCD1.35c, y5043, y0046, YP_pCD48;
OS   Yersinia pestis.
OG   Plasmid pCD1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM5 / Biovar Mediaevalis;
RX   PubMed=9746557; DOI=10.1128/iai.66.10.4611-4623.1998;
RA   Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA   Blattner F.R.;
RT   "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT   Yersinia pestis KIM5.";
RL   Infect. Immun. 66:4611-4623(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM5 / Biovar Mediaevalis;
RX   PubMed=9748454; DOI=10.1128/jb.180.19.5192-5202.1998;
RA   Hu P., Elliott J., McCready P., Skowronski E., Garnes J., Kobayashi A.,
RA   Brubaker R.R., Garcia E.;
RT   "Structural organization of virulence-associated plasmids of Yersinia
RT   pestis.";
RL   J. Bacteriol. 180:5192-5202(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
RN   [5]
RP   FUNCTION, SUBUNIT, AND SUBCELLULAR LOCATION.
RC   STRAIN=KIM8;
RX   PubMed=10714987; DOI=10.1128/jb.182.7.1834-1843.2000;
RA   Day J.B., Plano G.V.;
RT   "The Yersinia pestis YscY protein directly binds YscX, a secreted component
RT   of the type III secretion machinery.";
RL   J. Bacteriol. 182:1834-1843(2000).
CC   -!- FUNCTION: Required for Yop secretion. Functions probably as a chaperone
CC       which stabilizes YscX within the cell, before its secretion.
CC       {ECO:0000269|PubMed:10714987}.
CC   -!- SUBUNIT: Binds to YscX. {ECO:0000269|PubMed:10714987}.
CC   -!- INTERACTION:
CC       P61417; O15162: PLSCR1; Xeno; NbExp=2; IntAct=EBI-20592244, EBI-740019;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10714987}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF074612; AAC69796.1; -; Genomic_DNA.
DR   EMBL; AF053946; AAC62570.1; -; Genomic_DNA.
DR   EMBL; AL117189; CAB54912.1; -; Genomic_DNA.
DR   EMBL; AE017043; AAS58567.1; -; Genomic_DNA.
DR   PIR; T43590; T43590.
DR   RefSeq; NP_395169.1; NC_003131.1.
DR   RefSeq; NP_857747.1; NC_004836.1.
DR   RefSeq; NP_857942.1; NC_004839.1.
DR   RefSeq; WP_002229791.1; NZ_WUCM01000070.1.
DR   AlphaFoldDB; P61417; -.
DR   SMR; P61417; -.
DR   IntAct; P61417; 12.
DR   MINT; P61417; -.
DR   STRING; 214092.5832455; -.
DR   DNASU; 1149306; -.
DR   EnsemblBacteria; AAS58567; AAS58567; YP_pCD48.
DR   GeneID; 66841113; -.
DR   KEGG; ype:YPCD1.35c; -.
DR   KEGG; ypm:YP_pCD48; -.
DR   PATRIC; fig|214092.21.peg.46; -.
DR   eggNOG; COG0457; Bacteria.
DR   HOGENOM; CLU_170441_0_0_6; -.
DR   OMA; GWLQLQY; -.
DR   Proteomes; UP000000815; Plasmid pCD1.
DR   Proteomes; UP000001019; Plasmid pCD1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR016684; T3SS_YscY.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PIRSF; PIRSF017117; T3SS_YscY; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   1: Evidence at protein level;
KW   Chaperone; Cytoplasm; Plasmid; Reference proteome.
FT   CHAIN           1..114
FT                   /note="Chaperone protein YscY"
FT                   /id="PRO_0000066502"
SQ   SEQUENCE   114 AA;  13117 MW;  2DB6D15868E5124E CRC64;
     MNITLTKRQQ EFLLLNGWLQ LQCGHAERAC ILLDALLTLN PEHLAGRRCR LVALLNNNQG
     ERAEKEAQWL ISHDPLQAGN WLCLSRAQQL NGDLDKARHA YQHYLELKDH NESP