ID   YSL14_ORYSJ             Reviewed;         727 AA.
AC   Q6H7J6; Q0DZB5; Q3V7B7;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Probable metal-nicotianamine transporter YSL14;
DE   AltName: Full=Protein YELLOW STRIPE LIKE 14;
DE            Short=OsYSL14;
GN   Name=YSL14; OrderedLocusNames=Os02g0633300, LOC_Os02g42220;
GN   ORFNames=OJ1643_A10.18;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP   NOMENCLATURE.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15255870; DOI=10.1111/j.1365-313x.2004.02146.x;
RA   Koike S., Inoue H., Mizuno D., Takahashi M., Nakanishi H., Mori S.,
RA   Nishizawa N.K.;
RT   "OsYSL2 is a rice metal-nicotianamine transporter that is regulated by iron
RT   and expressed in the phloem.";
RL   Plant J. 39:415-424(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   TISSUE SPECIFICITY.
RX   PubMed=19049971; DOI=10.1074/jbc.m806042200;
RA   Inoue H., Kobayashi T., Nozoye T., Takahashi M., Kakei Y., Suzuki K.,
RA   Nakazono M., Nakanishi H., Mori S., Nishizawa N.K.;
RT   "Rice OsYSL15 is an iron-regulated iron(III)-deoxymugineic acid Transporter
RT   expressed in the roots and is essential for iron uptake in early growth of
RT   the seedlings.";
RL   J. Biol. Chem. 284:3470-3479(2009).
CC   -!- FUNCTION: May be involved in the transport of nicotianamine-chelated
CC       metals. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in leaves and at low levels in roots.
CC       {ECO:0000269|PubMed:15255870, ECO:0000269|PubMed:19049971}.
CC   -!- SIMILARITY: Belongs to the YSL (TC 2.A.67.2) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF09423.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB164645; BAE44205.1; -; mRNA.
DR   EMBL; AP004192; BAD25303.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF09423.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015625646.1; XM_015770160.1.
DR   AlphaFoldDB; Q6H7J6; -.
DR   STRING; 4530.OS02T0633300-01; -.
DR   PaxDb; Q6H7J6; -.
DR   PRIDE; Q6H7J6; -.
DR   GeneID; 9267947; -.
DR   KEGG; osa:9267947; -.
DR   InParanoid; Q6H7J6; -.
DR   OrthoDB; 525938at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR004813; OPT.
DR   InterPro; IPR045035; YSL-like.
DR   PANTHER; PTHR31645; PTHR31645; 1.
DR   Pfam; PF03169; OPT; 1.
DR   TIGRFAMs; TIGR00728; OPT_sfam; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..727
FT                   /note="Probable metal-nicotianamine transporter YSL14"
FT                   /id="PRO_0000363877"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        256..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        314..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        359..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        432..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        460..480
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        492..512
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        546..566
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        604..624
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        646..666
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        681..701
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        5
FT                   /note="T -> S (in Ref. 1; BAE44205)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        47..49
FT                   /note="GGG -> RGR (in Ref. 1; BAE44205)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   727 AA;  78494 MW;  04DBF9375C381B21 CRC64;
     MAQHTAAAAG GDEEVAEAEA AAAAAAGSTL RHRHAGKGAE EHEAAGGGGG GRNGGADDPD
     ATSVERVFAD KAVPSWREQL TLRAFVVSAL LAVMFSVIVM KLNLTTGIIP SLNVSAGLLG
     FFFVRLWTSA VERIGLLKQP FTRQENTVIQ TCVVSAYGIA FSGGFGSYLF GMSETIAKQA
     TEAKDAQNIK DPHLGWMIGF LFLVSFIGLF ALVPLRKIMI VDYKLTYPSG TATAYLINGF
     HTPEGAKLAK KQVKTLGKYF LFSFFWGFFQ WFYTAGDDCG FKNFPTLGLE AYNNRFFFDF
     SPTYVGVGMI CPYIVNVSVL LGGILSWGVM WPLIAKKKGS WYPADISDNS LHGLQAYRVF
     ISIALILGDG LYNFLKVLIR TIAGFISMVQ NNSKGMLPVS DNGMSMSTAE EVSFDDERRT
     EIFLKDQIPK SVAYGGYVVV AALSIGTLPE IFPQLKWYYI LVAYIVAPVL AFCNAYGSGL
     TDWSLASTYG KLAIFVFGAW AGLSHGGVLV GLAACGVMMS IVSTASDLMQ DFKTGYLTLA
     SPRSMFISQV IGTGMGCVIA PCVFWLFYKA FSNIGTSGTE YPAPYAIVYR NMAILGVDGF
     NSLPENCLTL CYIFFAAAIA INLIRDLAPH KVSRFIPLPM AMAIPFYIGS YFAIDMFLGS
     VILFVWEKLN KAKADAFGPA VASGLICGDG IWTLPQSILA LAKVKPPICM KFLSRAANAK
     VDSFLAG