YSL15_ORYSJ
ID YSL15_ORYSJ Reviewed; 672 AA.
AC Q6H3Z3; A0A0P0VMC8; Q0DZ37;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Iron-phytosiderophore transporter YSL15;
DE AltName: Full=Protein YELLOW STRIPE LIKE 15;
DE Short=OsYSL15;
GN Name=YSL15; OrderedLocusNames=Os02g0650300, LOC_Os02g43410;
GN ORFNames=OSJNBb0012J10.10-1, P0048B08.34-1;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], INDUCTION, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Nipponbare;
RX PubMed=15255870; DOI=10.1111/j.1365-313x.2004.02146.x;
RA Koike S., Inoue H., Mizuno D., Takahashi M., Nakanishi H., Mori S.,
RA Nishizawa N.K.;
RT "OsYSL2 is a rice metal-nicotianamine transporter that is regulated by iron
RT and expressed in the phloem.";
RL Plant J. 39:415-424(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE,
RP AND INDUCTION.
RX PubMed=19049971; DOI=10.1074/jbc.m806042200;
RA Inoue H., Kobayashi T., Nozoye T., Takahashi M., Kakei Y., Suzuki K.,
RA Nakazono M., Nakanishi H., Mori S., Nishizawa N.K.;
RT "Rice OsYSL15 is an iron-regulated iron(III)-deoxymugineic acid Transporter
RT expressed in the roots and is essential for iron uptake in early growth of
RT the seedlings.";
RL J. Biol. Chem. 284:3470-3479(2009).
CC -!- FUNCTION: Involved in Fe(3+) uptake from the rhizosphere and phloem
CC transport of iron. Plays an important role in iron homeostasis during
CC the early stages of growth. Transports Fe(3+)-phytosiderophore, but not
CC Fe(3+)- or Fe(2+)-nicotianamine. May not transport other chelated
CC metals. {ECO:0000269|PubMed:19049971}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:19049971};
CC Multi-pass membrane protein {ECO:0000305|PubMed:19049971}.
CC -!- TISSUE SPECIFICITY: Expressed in root phloem and at low levels in the
CC shoot companion cells. {ECO:0000269|PubMed:19049971}.
CC -!- DEVELOPMENTAL STAGE: Before anthesis, expressed in the vascular bundles
CC of spikelets, stamens, pistils, and husk. After fertilization,
CC expressed in the husk, spikelets, and pistil. From 3 to 10 days after
CC anthesis, expressed in the dorsal vascular bundles of developing
CC ovaries. At 15 days after anthesis, expressed in the embryo and dorsal
CC vascular bundles. At 30 days after anthesis, expressed in the scutellum
CC and endosperm. {ECO:0000269|PubMed:19049971}.
CC -!- INDUCTION: In roots by iron deficiency. {ECO:0000269|PubMed:15255870,
CC ECO:0000269|PubMed:19049971}.
CC -!- SIMILARITY: Belongs to the YSL (TC 2.A.67.2) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF09501.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB190923; BAE91893.1; -; mRNA.
DR EMBL; AP004868; BAD25586.1; -; Genomic_DNA.
DR EMBL; AP007203; BAD26556.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF09501.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; BAS80048.1; -; Genomic_DNA.
DR RefSeq; XP_015623627.1; XM_015768141.1.
DR AlphaFoldDB; Q6H3Z3; -.
DR STRING; 4530.OS02T0650300-01; -.
DR PaxDb; Q6H3Z3; -.
DR PRIDE; Q6H3Z3; -.
DR EnsemblPlants; Os02t0650300-01; Os02t0650300-01; Os02g0650300.
DR GeneID; 9268232; -.
DR Gramene; Os02t0650300-01; Os02t0650300-01; Os02g0650300.
DR KEGG; osa:9268232; -.
DR eggNOG; ENOG502QQ2H; Eukaryota.
DR HOGENOM; CLU_015477_2_0_1; -.
DR InParanoid; Q6H3Z3; -.
DR OMA; CVIETCA; -.
DR OrthoDB; 525938at2759; -.
DR PlantReactome; R-OSA-8858053; Polar auxin transport.
DR PlantReactome; R-OSA-9025727; Iron uptake and transport in root vascular system.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR ExpressionAtlas; Q6H3Z3; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0051980; F:iron-nicotianamine transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0010039; P:response to iron ion; IBA:GO_Central.
DR GO; GO:0048316; P:seed development; IBA:GO_Central.
DR InterPro; IPR004813; OPT.
DR InterPro; IPR045035; YSL-like.
DR PANTHER; PTHR31645; PTHR31645; 1.
DR Pfam; PF03169; OPT; 1.
DR TIGRFAMs; TIGR00728; OPT_sfam; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Ion transport; Iron; Iron transport; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..672
FT /note="Iron-phytosiderophore transporter YSL15"
FT /id="PRO_0000363878"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 390..410
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 418..438
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 450..470
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 504..524
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 556..576
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 602..622
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 630..650
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 672 AA; 73150 MW; E61C4C257CE76D4E CRC64;
MEHADADRTR VAPEIGSLHD EDAEADPARA REMERLQPWR EQVTARGVVA AALIGFVFSV
IVMKIALTTG LVPTLNISAA LLAFLALRGW TRALERLGFS PRPFTRQENT VVQTCAVACY
TIAFGGGFGS TLLGLNKRTY ELAGNSPGNV PGSYKEPGIG WMVGLLLAIS FAGNLSLIPL
RKALVVDYKL TYPSGTATAV LINGFHTAQG DKNAKLQLHG FLKYFGLSLF WSFFQWFYTG
GNACGFVQFP TFGLKAWKQS FFFDFSLTYV GAGMICSHLV NLSTLLGAVI SWGIMWPLIS
KHKGDWYPAN IPESSMTSLY GYKSFLCIAL IMGDGLYHFV KVTGVTAKSL HNRFNRKSVS
NTASEEGDMV SLDDLQRDEV FKRGTVPSWM AYSGYFLLSI IAVITIPIMF RQVKWYYVII
AYALGPVLGF ANSYGAGLTD INMGYNYGKI ALFVFAAWAG KDNGVIAGLV VGTLVKQLVL
VSADLMHDLK TGHLTLTSPR SMLVGELIGT GIGCFIAPLT FMLFYRAFDI GNPDGYWKAP
YALIYRNMAI LGIEGISALP KHCLSLSVGF FAFAVLTNVA RDALPARYKK LVPLPTAMAV
PFLVGASFAI DMCVGSLVLF AWNKMNKKEA AFMVPAVASG LMCGDGIWTF PSSILALAKI
KPPICMKFTP GS
