YSL4_ARATH
ID YSL4_ARATH Reviewed; 670 AA.
AC Q6R3K8; Q9FLM9;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Probable metal-nicotianamine transporter YSL4;
DE AltName: Full=Protein YELLOW STRIPE LIKE 4;
DE Short=AtYSL4;
GN Name=YSL4; OrderedLocusNames=At5g41000; ORFNames=MEE6.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Roberts L.A., Walker E.L.;
RT "The yellow stripe-like (YSL) family of metal-nicotianamine transporters.";
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP DEVELOPMENTAL STAGE.
RX PubMed=12114572; DOI=10.1104/pp.011024;
RA Hanaoka H., Noda T., Shirano Y., Kato T., Hayashi H., Shibata D.,
RA Tabata S., Ohsumi Y.;
RT "Leaf senescence and starvation-induced chlorosis are accelerated by the
RT disruption of an Arabidopsis autophagy gene.";
RL Plant Physiol. 129:1181-1193(2002).
CC -!- FUNCTION: May be involved in the transport of nicotianamine-chelated
CC metals. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Induced during senescence.
CC {ECO:0000269|PubMed:12114572}.
CC -!- MISCELLANEOUS: Up-regulated in autophagy mutant.
CC -!- SIMILARITY: Belongs to the YSL (TC 2.A.67.2) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB09702.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY515562; AAS00693.1; -; mRNA.
DR EMBL; AB010072; BAB09702.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED94624.1; -; Genomic_DNA.
DR RefSeq; NP_198916.2; NM_123465.4.
DR AlphaFoldDB; Q6R3K8; -.
DR STRING; 3702.AT5G41000.1; -.
DR PaxDb; Q6R3K8; -.
DR PRIDE; Q6R3K8; -.
DR ProteomicsDB; 242354; -.
DR EnsemblPlants; AT5G41000.1; AT5G41000.1; AT5G41000.
DR GeneID; 834102; -.
DR Gramene; AT5G41000.1; AT5G41000.1; AT5G41000.
DR KEGG; ath:AT5G41000; -.
DR Araport; AT5G41000; -.
DR TAIR; locus:2163036; AT5G41000.
DR eggNOG; ENOG502QQ2H; Eukaryota.
DR HOGENOM; CLU_015477_2_0_1; -.
DR InParanoid; Q6R3K8; -.
DR OMA; IIKITIV; -.
DR OrthoDB; 525938at2759; -.
DR PhylomeDB; Q6R3K8; -.
DR PRO; PR:Q6R3K8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q6R3K8; baseline and differential.
DR Genevisible; Q6R3K8; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
DR GO; GO:0005774; C:vacuolar membrane; IBA:GO_Central.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0034755; P:iron ion transmembrane transport; IGI:TAIR.
DR InterPro; IPR004813; OPT.
DR InterPro; IPR045035; YSL-like.
DR PANTHER; PTHR31645; PTHR31645; 1.
DR Pfam; PF03169; OPT; 1.
DR TIGRFAMs; TIGR00728; OPT_sfam; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..670
FT /note="Probable metal-nicotianamine transporter YSL4"
FT /id="PRO_0000311415"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 318..338
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 416..436
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 450..470
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 507..527
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 559..579
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 601..621
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 636..656
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 670 AA; 73575 MW; F5EF139338DE236D CRC64;
METEIPRSTE ISETLLLPET NLDHGEYVPE WKEQITIRGL ISSALLGILF CIITHKLNLT
IGIIPSLNVA AGLLGFFFIK SWTGFLSKLG FLSKPFTKQE NTVIQTCVVS CYGLAYSGGF
GSYLIAMDER TYKLIGSDYP GNNPEDVINP GLWWMTGFLF VVSFLGLFCL VPLRKVMILD
YKLTYPSGTA TAMLINSFHN NTGAELAGKQ VKCLGKYLSL SLVWSCFKWF FSGIGGACGF
DHFPTLGLTL FKNTFYFDFS PTFIGCGMIC PHLVNCSVLL GAIISWGFLW PFISQHAGDW
YPADLKANDF KGLYGYKVFI AISIILGDGL YNLIKIIVVT VKEICNKSSR QHNLPVFTDI
LDKSKTSVLM REKKKRDIIF LKDRIPLEFA VSGYVGLAAI STAIIPLIFP PLKWYFVLCS
YLVAPGLAFC NSYGAGLTDM SMPSTYGKTG LFIVASIVGN NGGVIAGLAA CGIMMSIVST
AADLMQDFKT GYLTLSSAKS MFVTQLLGTA MGCIIAPLTF WLFWTAFDIG DPDGLYKAPY
AVIYREMAIL GVEGFAKLPK HCLALCCGFF IAALIVNLIR DMTPPKISKL IPLPMAMAGP
FYIGAYFAID MFVGTVIMLV WERMNKKDAD DYSGAVASGL ICGDGIWTIP SAILSILRIN
PPICMYFRPS
