YSL5_ARATH
ID YSL5_ARATH Reviewed; 714 AA.
AC Q9LUN2; Q93ZI8;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Probable metal-nicotianamine transporter YSL5;
DE AltName: Full=Protein YELLOW STRIPE LIKE 5;
DE Short=AtYSL5;
GN Name=YSL5; OrderedLocusNames=At3g17650; ORFNames=MKP6.21, MKP6_20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Roberts L.A., Walker E.L.;
RT "The yellow stripe-like (YSL) family of metal-nicotianamine transporters.";
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: May be involved in the transport of nicotianamine-chelated
CC metals. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the YSL (TC 2.A.67.2) family. {ECO:0000305}.
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DR EMBL; AY515563; AAS00694.1; -; mRNA.
DR EMBL; AB022219; BAB02055.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75985.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM63670.1; -; Genomic_DNA.
DR EMBL; AY057503; AAL09744.1; -; mRNA.
DR EMBL; BT001087; AAN46868.1; -; mRNA.
DR RefSeq; NP_001325744.1; NM_001338296.1.
DR RefSeq; NP_566584.1; NM_112646.2.
DR AlphaFoldDB; Q9LUN2; -.
DR SMR; Q9LUN2; -.
DR BioGRID; 6365; 9.
DR IntAct; Q9LUN2; 9.
DR STRING; 3702.AT3G17650.1; -.
DR iPTMnet; Q9LUN2; -.
DR PaxDb; Q9LUN2; -.
DR PRIDE; Q9LUN2; -.
DR ProteomicsDB; 242921; -.
DR EnsemblPlants; AT3G17650.1; AT3G17650.1; AT3G17650.
DR EnsemblPlants; AT3G17650.2; AT3G17650.2; AT3G17650.
DR GeneID; 821032; -.
DR Gramene; AT3G17650.1; AT3G17650.1; AT3G17650.
DR Gramene; AT3G17650.2; AT3G17650.2; AT3G17650.
DR KEGG; ath:AT3G17650; -.
DR Araport; AT3G17650; -.
DR TAIR; locus:2090502; AT3G17650.
DR eggNOG; ENOG502QUDW; Eukaryota.
DR HOGENOM; CLU_015477_2_0_1; -.
DR InParanoid; Q9LUN2; -.
DR OMA; FVQLRGP; -.
DR OrthoDB; 525938at2759; -.
DR PhylomeDB; Q9LUN2; -.
DR PRO; PR:Q9LUN2; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LUN2; baseline and differential.
DR Genevisible; Q9LUN2; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004813; OPT.
DR InterPro; IPR045035; YSL-like.
DR PANTHER; PTHR31645; PTHR31645; 1.
DR Pfam; PF03169; OPT; 1.
DR TIGRFAMs; TIGR00728; OPT_sfam; 1.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..714
FT /note="Probable metal-nicotianamine transporter YSL5"
FT /id="PRO_0000311416"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 236..256
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 295..315
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 413..433
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 445..465
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 477..497
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 531..551
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 593..613
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 631..651
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 17..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 224
FT /note="P -> T (in Ref. 4; AAN46868/AAL09744)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 714 AA; 78853 MW; 90E225664BF55EEB CRC64;
MRKGVLNPDR DRQIVEHELQ ETGFSPETEK VKNKNFEEDE EEEDESVEKI FESREVPSWK
KQLTVRAFVV SFMLSILFSF IVMKLNLTTG IIPSLNVSAG LLGFFFVKTW TKMLHRSGLL
KQPFTRQENT VIQTCVVASS GIAFSGGFGT YLFGMSERIA TQSGDVSRGV KDPSLGWIIG
FLFVVSFLGL FSVVPLRKIM VIDFKLTYPS GTATAHLINS FHTPQGAKLA KKQVRVLGKF
FSLSFFWSFF QWFFTGGENC GFSNFPTFGL KAYQYKFYFD FSATYVGVGM ICPYIINISV
LLGGILSWGI MWPLIETKKG DWFPDNVPSS SMHGLQAYKV FIAVAIILGD GLYNFCKVLS
RTLSGLFVQL RGPTTSISRT SFTLEEDPHA SPLSPKQSYD DQRRTRFFLK DQIPTWFAVG
GYITIAATST AILPHMFHQL RWYYILVIYI CAPVLAFCNA YGAGLTDWSL ASTYGKLAIF
TIGAWAGSEH GGMLAGLAAC GVMMNIVSTA SDLTQDFKTG YLTLSSPKSM FVSQVIGTAM
GCVVSPCVFW LFYKAFDDLG LPNTEYPAPF ATVYRSMAKL GVEGVASLPR ECLVLCYAFF
GVAILVNIVK DSLHSNWGRF IPLPMAMAIP FFLGPYFAID MCVGSLILFI WERVDAAKAE
AFGTAVASGL ICGDGIWSLP SSVLAIAGVN PPVCMKFLSS ATNSKVDNFL KGSI
