YSL6_ARATH
ID YSL6_ARATH Reviewed; 676 AA.
AC Q6R3K6; Q8L859; Q8LB74; Q9LSD4;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2007, sequence version 2.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Probable metal-nicotianamine transporter YSL6;
DE AltName: Full=Protein YELLOW STRIPE LIKE 6;
DE Short=AtYSL6;
GN Name=YSL6; OrderedLocusNames=At3g27020; ORFNames=MOJ10.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Roberts L.A., Walker E.L.;
RT "The yellow stripe-like (YSL) family of metal-nicotianamine transporters.";
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the transport of nicotianamine-chelated
CC metals. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- MISCELLANEOUS: Was also erroneously assigned to At3g27010.
CC {ECO:0000305|PubMed:14593172}.
CC -!- SIMILARITY: Belongs to the YSL (TC 2.A.67.2) family. {ECO:0000305}.
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DR EMBL; AY515564; AAS00695.1; -; mRNA.
DR EMBL; AB026649; BAB01083.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77255.1; -; Genomic_DNA.
DR EMBL; AY120725; AAM53283.1; -; mRNA.
DR EMBL; AY087380; AAM64930.1; -; mRNA.
DR RefSeq; NP_566806.1; NM_113616.3.
DR AlphaFoldDB; Q6R3K6; -.
DR STRING; 3702.AT3G27020.1; -.
DR PaxDb; Q6R3K6; -.
DR PRIDE; Q6R3K6; -.
DR ProteomicsDB; 242345; -.
DR EnsemblPlants; AT3G27020.1; AT3G27020.1; AT3G27020.
DR GeneID; 822319; -.
DR Gramene; AT3G27020.1; AT3G27020.1; AT3G27020.
DR KEGG; ath:AT3G27020; -.
DR Araport; AT3G27020; -.
DR TAIR; locus:2091970; AT3G27020.
DR eggNOG; ENOG502QQ2H; Eukaryota.
DR HOGENOM; CLU_015477_2_0_1; -.
DR InParanoid; Q6R3K6; -.
DR OMA; AGNQVRQ; -.
DR OrthoDB; 525938at2759; -.
DR PhylomeDB; Q6R3K6; -.
DR PRO; PR:Q6R3K6; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q6R3K6; baseline and differential.
DR Genevisible; Q6R3K6; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
DR GO; GO:0009526; C:plastid envelope; IDA:TAIR.
DR GO; GO:0005774; C:vacuolar membrane; IBA:GO_Central.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0034755; P:iron ion transmembrane transport; IGI:TAIR.
DR InterPro; IPR004813; OPT.
DR InterPro; IPR045035; YSL-like.
DR PANTHER; PTHR31645; PTHR31645; 1.
DR Pfam; PF03169; OPT; 1.
DR TIGRFAMs; TIGR00728; OPT_sfam; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..676
FT /note="Probable metal-nicotianamine transporter YSL6"
FT /id="PRO_0000311417"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 321..341
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 392..412
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 413..433
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 510..530
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 561..581
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 604..624
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 639..659
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 111
FT /note="V -> VVA (in Ref. 1; AAS00695)"
FT /evidence="ECO:0000305"
FT CONFLICT 241..247
FT /note="CGFDNFP -> WELKLT (in Ref. 1; AAS00695)"
FT /evidence="ECO:0000305"
FT CONFLICT 260
FT /note="F -> L (in Ref. 5; AAM64930)"
FT /evidence="ECO:0000305"
FT CONFLICT 263
FT /note="S -> R (in Ref. 4; AAM53283)"
FT /evidence="ECO:0000305"
FT CONFLICT 462
FT /note="G -> E (in Ref. 1; AAS00695)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 676 AA; 73573 MW; 1DA93272E4AB2A87 CRC64;
MGTEIPRSAE ISEALLPPES EKTVTATEEH VPEWKEQITI RGLTVSALLG TLFCIITHKL
NLTVGIIPSL NVAAGLLGFF FVKSWTGFLS KLGFTVKPFT KQENTVIQTC VVACYGLAFS
GGFGSYLIAM DEKTYKLIGA DYPGNHAEDV INPGLWWMIG FLFVVSFLGL FSLVPLRKVM
VLDYKLTYPS GTATAMLINS FHTNTGAELA GNQVKCLGKY LSLSLIWSCF KWFFSGIGDA
CGFDNFPTLG LTLFKNTFYF DFSPTYIGCG LICPHIVNCS VLLGAIISWG ILWPFVSQHA
GDWYPADLGS NDFKGLYGYK VFIAIAIILG DGLYNLVKII AVTVKELCSS RSRRLNLPIV
TDGVDDSEAS EILLVKKKRD EVFLKDRIPL EFAIAGYVGL AAISTATIPI IFPPLKWYFV
LCSYFIAPAL AFCNSYGTGL TDWSLASTYG KIGLFIIASV VGSDGGVIAG LAACGVMMSI
VSTAADLMQD FKTGYLTLSS AKSMFVSQLV GTAMGCVIAP LTFWLFWTAF DIGDPNGPYK
APYAVIFREM AILGIEGFAE LPKHCLALCY GFFIAALIVN LLRDITPPKI SQFIPIPMAM
AVPFYIGAYF AIDMFVGTVI LFVWERINRK DAEDFAGAVA SGLICGDGIW TIPSAILSIL
RINPPICMYF GPSSAR