YSL6_ORYSJ
ID YSL6_ORYSJ Reviewed; 678 AA.
AC Q7XRV2; A3ATA0; Q25CI0;
DT 03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Probable metal-nicotianamine transporter YSL6;
DE AltName: Full=Protein YELLOW STRIPE LIKE 6;
DE Short=OsYSL6;
GN Name=YSL6; OrderedLocusNames=Os04g0390500, LOC_Os04g32050;
GN ORFNames=OsJ_014022, OSJNBa0055C08.1;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Nipponbare;
RX PubMed=15255870; DOI=10.1111/j.1365-313x.2004.02146.x;
RA Koike S., Inoue H., Mizuno D., Takahashi M., Nakanishi H., Mori S.,
RA Nishizawa N.K.;
RT "OsYSL2 is a rice metal-nicotianamine transporter that is regulated by iron
RT and expressed in the phloem.";
RL Plant J. 39:415-424(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [8]
RP TISSUE SPECIFICITY.
RX PubMed=19049971; DOI=10.1074/jbc.m806042200;
RA Inoue H., Kobayashi T., Nozoye T., Takahashi M., Kakei Y., Suzuki K.,
RA Nakazono M., Nakanishi H., Mori S., Nishizawa N.K.;
RT "Rice OsYSL15 is an iron-regulated iron(III)-deoxymugineic acid Transporter
RT expressed in the roots and is essential for iron uptake in early growth of
RT the seedlings.";
RL J. Biol. Chem. 284:3470-3479(2009).
CC -!- FUNCTION: May be involved in the transport of nicotianamine-chelated
CC metals. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots and leaves.
CC {ECO:0000269|PubMed:15255870, ECO:0000269|PubMed:19049971}.
CC -!- SIMILARITY: Belongs to the YSL (TC 2.A.67.2) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF14554.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB190916; BAE91886.1; -; mRNA.
DR EMBL; AL731600; CAE02278.1; -; Genomic_DNA.
DR EMBL; AP008210; BAF14554.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014960; BAS88960.1; -; Genomic_DNA.
DR EMBL; CM000141; EAZ30539.1; -; Genomic_DNA.
DR EMBL; AK100148; BAG94466.1; -; mRNA.
DR RefSeq; XP_015635791.1; XM_015780305.1.
DR AlphaFoldDB; Q7XRV2; -.
DR STRING; 4530.OS04T0390500-02; -.
DR PaxDb; Q7XRV2; -.
DR PRIDE; Q7XRV2; -.
DR EnsemblPlants; Os04t0390500-02; Os04t0390500-02; Os04g0390500.
DR EnsemblPlants; Os04t0390500-03; Os04t0390500-03; Os04g0390500.
DR GeneID; 4335676; -.
DR Gramene; Os04t0390500-02; Os04t0390500-02; Os04g0390500.
DR Gramene; Os04t0390500-03; Os04t0390500-03; Os04g0390500.
DR KEGG; osa:4335676; -.
DR eggNOG; ENOG502QQ2H; Eukaryota.
DR InParanoid; Q7XRV2; -.
DR OMA; AGNQVRQ; -.
DR OrthoDB; 525938at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000007752; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR ExpressionAtlas; Q7XRV2; baseline and differential.
DR Genevisible; Q7XRV2; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005774; C:vacuolar membrane; IBA:GO_Central.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004813; OPT.
DR InterPro; IPR045035; YSL-like.
DR PANTHER; PTHR31645; PTHR31645; 1.
DR Pfam; PF03169; OPT; 1.
DR TIGRFAMs; TIGR00728; OPT_sfam; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..678
FT /note="Probable metal-nicotianamine transporter YSL6"
FT /id="PRO_0000363869"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 324..344
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 394..414
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 419..439
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 467..487
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 512..532
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 561..581
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 606..626
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 641..661
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 22..24
FT /note="GGD -> AGN (in Ref. 6; EAZ30539)"
FT /evidence="ECO:0000305"
FT CONFLICT 31..32
FT /note="VE -> LK (in Ref. 6; EAZ30539)"
FT /evidence="ECO:0000305"
FT CONFLICT 572
FT /note="S -> L (in Ref. 1; BAE91886)"
FT /evidence="ECO:0000305"
FT CONFLICT 577
FT /note="A -> V (in Ref. 1; BAE91886)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 678 AA; 73322 MW; 71BA00F84A6A563B CRC64;
MGSVADDAEI TGPLLAAAAG GGGDSAAAAG VERVPAWREQ VTVRGIVVSA VLGVLFCLIT
HKLNLTVGVI PSLNVSAGLL GYFLVRSWTA VLGRLGFVIA PFTKQENTVI QTCVVACYGL
AFSGGFGSYM LAMDQKTYEL IGPDYPGNRA IDVMNPSLGW MIGFMFVVSF LGLFSLVALR
KVMVIDYKLT YPSGTATAML INSFHTTSGA ELAEKQVSCL GKYLSISFFW NCFKWFFSGV
GDSCGFDNFP SLGLAAFKNT FYFDFSPTYI GCGLICPHIV NCSTLLGAII SWGFLWPYIS
TKAGDWYPAN LGSNDFKGLY GYKVFISVSV ILGDGLYNLI KIIYATIKEV MNARSKQGRL
PLVRVHDDDE GSKLSAEEKL RNDTFLKDRI PSWLAGSGYV GLAAISTATV PMIFPQVKWY
LVLCAYVVAP LLAFCNSYGC GLTDWNLAST YGKIGLFIFA SLVGRSGGVI AGLAACGVMM
SIVSTAADLM QDFRTGYLTL SSPRSMFVSQ LIGTTLGCII APLTFWLYWT AFDIGNPDGM
FKAPYAVIYR EMSILGVEGF SALPQHCLAI CSVFFVAAIL INLLRDVTPK SVSKFIPLPM
AMAVPFYIGA YFAIDMFVGT VILFVWERVN RKESEDFAGA IASGLICGDG IWSVPSAILS
IMRIDPPMCM YFKPSLTS
