ID   YSNF1_PLAF7             Reviewed;         229 AA.
AC   Q8IL52; A0A144A3Q5;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 2.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Putative vacuolar protein sorting-associated protein 60 {ECO:0000305};
GN   Name=VPS60; ORFNames=PF14_0397, PF3D7_1441800;
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3D7;
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000305}
RP   SYNTHESIS OF 17-45, AND POSSIBLE CANDIDATE MALARIA EPITOPE.
RX   PubMed=17653272; DOI=10.1371/journal.pone.0000645;
RA   Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I.,
RA   Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F.,
RA   Baecker V., Druilhe P., Kajava A.V., Corradin G.;
RT   "Rapid identification of malaria vaccine candidates based on alpha-helical
RT   coiled coil protein motif.";
RL   PLoS ONE 2:E645-E645(2007).
CC   -!- BIOTECHNOLOGY: Possible candidate for an effective malaria vaccine as
CC       determined by epitope response in sera. {ECO:0000269|PubMed:17653272}.
CC   -!- SIMILARITY: Belongs to the SNF7 family. {ECO:0000255}.
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DR   EMBL; LN999946; CZU00114.1; -; Genomic_DNA.
DR   RefSeq; XP_001348571.2; XM_001348535.2.
DR   AlphaFoldDB; Q8IL52; -.
DR   SMR; Q8IL52; -.
DR   STRING; 5833.PF14_0397; -.
DR   PRIDE; Q8IL52; -.
DR   EnsemblProtists; CZU00114; CZU00114; PF3D7_1441800.
DR   GeneID; 811979; -.
DR   KEGG; pfa:PF3D7_1441800; -.
DR   VEuPathDB; PlasmoDB:PF3D7_1441800; -.
DR   HOGENOM; CLU_1211870_0_0_1; -.
DR   InParanoid; Q8IL52; -.
DR   OMA; MEQAQTM; -.
DR   PhylomeDB; Q8IL52; -.
DR   Proteomes; UP000001450; Chromosome 14.
DR   GO; GO:0005771; C:multivesicular body; IBA:GO_Central.
DR   GO; GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IBA:GO_Central.
DR   GO; GO:0006900; P:vesicle budding from membrane; IBA:GO_Central.
DR   InterPro; IPR005024; Snf7_fam.
DR   PANTHER; PTHR22761; PTHR22761; 1.
DR   Pfam; PF03357; Snf7; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Merozoite; Reference proteome.
FT   CHAIN           1..229
FT                   /note="Putative vacuolar protein sorting-associated protein
FT                   60"
FT                   /id="PRO_0000371258"
FT   COILED          16..78
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   229 AA;  26757 MW;  D28DB11CAA06B3B2 CRC64;
     MKFFKGKKDK TLDEAYDTLE KSVKGIDENI EKYNKELNVI KQKIEEEKKK NPINQHIINS
     LRNKAANIIQ KKKVYENNKE STMGIQFNID QIKYANDNVQ LSIDTYKALK NTSKVLKKNI
     KKVNINKIEK LQDDLFDYIE DTKEIGNILS SSYDIPLNLD EQEIDAELAL IEDSILDENV
     EQDNIASYIE DDKKEEDKNL LQQIPVEEKN FDAIQQKTKK ETYFAQKES