ID   YSV5_CAEEL              Reviewed;         490 AA.
AC   Q10011;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   02-DEC-2020, sequence version 3.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Uncharacterized protein T19C3.5;
DE   Flags: Precursor;
GN   ORFNames=T19C3.5 {ECO:0000312|WormBase:T19C3.5};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-405, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=12754521; DOI=10.1038/nbt829;
RA   Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,
RA   Kasai K., Takahashi N., Isobe T.;
RT   "Lectin affinity capture, isotope-coded tagging and mass spectrometry to
RT   identify N-linked glycoproteins.";
RL   Nat. Biotechnol. 21:667-672(2003).
RN   [3]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-405, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RX   PubMed=15888633; DOI=10.1093/glycob/cwi075;
RA   Fan X., She Y.-M., Bagshaw R.D., Callahan J.W., Schachter H., Mahuran D.J.;
RT   "Identification of the hydrophobic glycoproteins of Caenorhabditis
RT   elegans.";
RL   Glycobiology 15:952-964(2005).
RN   [4]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-405 AND ASN-415, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA   Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA   Taoka M., Takahashi N., Isobe T.;
RT   "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT   elegans and suggests an atypical translocation mechanism for integral
RT   membrane proteins.";
RL   Mol. Cell. Proteomics 6:2100-2109(2007).
CC   -!- SIMILARITY: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
CC       {ECO:0000305}.
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DR   EMBL; BX284603; CCD73737.2; -; Genomic_DNA.
DR   PIR; T16889; T16889.
DR   RefSeq; NP_497222.1; NM_064821.3.
DR   AlphaFoldDB; Q10011; -.
DR   SMR; Q10011; -.
DR   STRING; 6239.T19C3.5; -.
DR   iPTMnet; Q10011; -.
DR   EPD; Q10011; -.
DR   PaxDb; Q10011; -.
DR   PeptideAtlas; Q10011; -.
DR   EnsemblMetazoa; T19C3.5.1; T19C3.5.1; WBGene00020563.
DR   UCSC; T19C3.5; c. elegans.
DR   WormBase; T19C3.5; CE54124; WBGene00020563; -.
DR   eggNOG; KOG4160; Eukaryota.
DR   GeneTree; ENSGT01020000230460; -.
DR   HOGENOM; CLU_044130_0_0_1; -.
DR   InParanoid; Q10011; -.
DR   OrthoDB; 1242894at2759; -.
DR   PhylomeDB; Q10011; -.
DR   Reactome; R-CEL-166016; Toll Like Receptor 4 (TLR4) Cascade.
DR   Reactome; R-CEL-5686938; Regulation of TLR by endogenous ligand.
DR   PRO; PR:Q10011; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00020563; Expressed in adult organism and 2 other tissues.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   InterPro; IPR017943; Bactericidal_perm-incr_a/b_dom.
DR   InterPro; IPR032942; BPI/LBP/Plunc.
DR   InterPro; IPR001124; Lipid-bd_serum_glycop_C.
DR   InterPro; IPR017942; Lipid-bd_serum_glycop_N.
DR   PANTHER; PTHR10504; PTHR10504; 1.
DR   Pfam; PF01273; LBP_BPI_CETP; 1.
DR   Pfam; PF02886; LBP_BPI_CETP_C; 1.
DR   SMART; SM00328; BPI1; 1.
DR   SMART; SM00329; BPI2; 1.
DR   SUPFAM; SSF55394; SSF55394; 2.
PE   1: Evidence at protein level;
KW   Disulfide bond; Glycoprotein; Reference proteome; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..490
FT                   /note="Uncharacterized protein T19C3.5"
FT                   /id="PRO_0000017173"
FT   CARBOHYD        32
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        145
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        271
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        369
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        405
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:12754521,
FT                   ECO:0000269|PubMed:15888633, ECO:0000269|PubMed:17761667"
FT   CARBOHYD        415
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:17761667"
FT   CARBOHYD        465
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        164..204
FT                   /evidence="ECO:0000250|UniProtKB:P17213"
SQ   SEQUENCE   490 AA;  54808 MW;  65BEC8DE60B20CA6 CRC64;
     MEKSVSGPNI FNMKLLLLLL ILTISFCYAF NNETLKVRLN VPFFKFFSKN GHHVVDEEIP
     KITIPEIRLP FSSSIGHGVV RTDDLKIEKF SSPKIDFKLS KTGINWWTTG GAIKLSGRWH
     AKFTEVITIR DKGWLNAYAT GIQMNISAAA YQLDGQPQVK IGDCTVQIQK LDVEIGGSVL
     SWLVNLFETP FSKLVKKVIN AQACSAAKGI LIEEANRFLH SLPSHVDVGA NFYVDYFLTQ
     NPHATSEFTE FDLAADIVYG KSLCHPINIG NWTDASSTPG MLTSWISVSI PNCLIHSAHQ
     NQLVKLLVSK DIPVVEPYLR TSCGFLGLCI GKFFKKLRNE YPNNHVDLFF HTYSTPYFVM
     SEKEGVMLNM SLAVDLFINP YAKTKQNILA RLVVDTFSTV EPFLNHTRIH GRLQNSTITA
     RVDFSNIGDI PKAFLSAFSS ILSMTAREAV RSVLGVGIPI PSYDNVTLAD SSTIEVFDQF
     LRANIDFEYK