YTAF_BACSU
ID YTAF_BACSU Reviewed; 210 AA.
AC C0SP79; O34547; Q795V6;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 1.
DT 03-AUG-2022, entry version 57.
DE RecName: Full=Probable sporulation protein YtaF {ECO:0000305};
GN Name=ytaF; OrderedLocusNames=BSU29070;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9387221; DOI=10.1099/00221287-143-11-3431;
RA Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.;
RT "Sequencing and functional annotation of the Bacillus subtilis genes in the
RT 200 kb rrnB-dnaB region.";
RL Microbiology 143:3431-3441(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP SEQUENCE REVISION TO N- AND C-TERMINUS.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
RN [4]
RP DEVELOPMENTAL STAGE, INDUCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=23396918; DOI=10.1128/jb.02110-12;
RA Abecasis A.B., Serrano M., Alves R., Quintais L., Pereira-Leal J.B.,
RA Henriques A.O.;
RT "A genomic signature and the identification of new sporulation genes.";
RL J. Bacteriol. 195:2101-2115(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the mother cell during sporulation.
CC {ECO:0000269|PubMed:23396918}.
CC -!- INDUCTION: Expression is regulated by the sporulation transcription
CC factor sigma E. {ECO:0000269|PubMed:23396918}.
CC -!- DISRUPTION PHENOTYPE: Disruption of the gene causes a 10-fold reduction
CC in the efficiency of sporulation. Mutants divide asymmetrically but
CC fail to complete engulfment of the forespore by the mother cell.
CC {ECO:0000269|PubMed:23396918}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC00352.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAC00352.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AF008220; AAC00352.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL009126; CAB14867.2; -; Genomic_DNA.
DR RefSeq; NP_390785.2; NC_000964.3.
DR RefSeq; WP_003229449.1; NZ_JNCM01000036.1.
DR AlphaFoldDB; C0SP79; -.
DR STRING; 224308.BSU29070; -.
DR PRIDE; C0SP79; -.
DR EnsemblBacteria; CAB14867; CAB14867; BSU_29070.
DR GeneID; 937389; -.
DR KEGG; bsu:BSU29070; -.
DR PATRIC; fig|224308.43.peg.3041; -.
DR eggNOG; COG1971; Bacteria.
DR OMA; VGITYGM; -.
DR PhylomeDB; C0SP79; -.
DR BioCyc; BSUB:BSU29070-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR InterPro; IPR003810; Mntp/YtaF.
DR InterPro; IPR014205; Spore_YtaF.
DR PANTHER; PTHR35529; PTHR35529; 1.
DR Pfam; PF02659; Mntp; 2.
DR TIGRFAMs; TIGR02840; spore_YtaF; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Sporulation; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..210
FT /note="Probable sporulation protein YtaF"
FT /id="PRO_0000389489"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 162..184
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 210 AA; 22773 MW; 0ECAAED023A5AD3D CRC64;
MQMVSILLLA LAVSLDSFSV GFTYGLRKMK IPFKAILVIA CCSGAVMFIS MLIGSFLTKF
FPVYVTEKLG GLILVGIGAW VLYQFFKPAK DKEYLLHEKT LLNLEVRSLG IVIHILRKPM
SADIDKSGVI NGIEAVLLGF ALSIDAFGAG IGAAILGFSP IVMSIAVAIM SSLFVSIGIN
AGHFLSKWKW IDKMAFLPGL LLITIGLWKL
