ID   YTCB_BACSU              Reviewed;         316 AA.
AC   O34886; Q795N4;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Uncharacterized UDP-glucose epimerase YtcB;
DE            EC=4.-.-.-;
GN   Name=ytcB; OrderedLocusNames=BSU30870;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9387221; DOI=10.1099/00221287-143-11-3431;
RA   Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.;
RT   "Sequencing and functional annotation of the Bacillus subtilis genes in the
RT   200 kb rrnB-dnaB region.";
RL   Microbiology 143:3431-3441(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000305}.
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DR   EMBL; AF008220; AAC00366.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15065.1; -; Genomic_DNA.
DR   PIR; H69988; H69988.
DR   RefSeq; NP_390965.1; NC_000964.3.
DR   RefSeq; WP_003229036.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O34886; -.
DR   SMR; O34886; -.
DR   STRING; 224308.BSU30870; -.
DR   PaxDb; O34886; -.
DR   PRIDE; O34886; -.
DR   EnsemblBacteria; CAB15065; CAB15065; BSU_30870.
DR   GeneID; 938900; -.
DR   KEGG; bsu:BSU30870; -.
DR   PATRIC; fig|224308.179.peg.3346; -.
DR   eggNOG; COG0451; Bacteria.
DR   InParanoid; O34886; -.
DR   OMA; GVRTSWG; -.
DR   PhylomeDB; O34886; -.
DR   BioCyc; BSUB:BSU30870-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome.
FT   CHAIN           1..316
FT                   /note="Uncharacterized UDP-glucose epimerase YtcB"
FT                   /id="PRO_0000360625"
FT   ACT_SITE        149
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         126
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   316 AA;  34912 MW;  D3F21B895536406B CRC64;
     MKILVTGAAG FIGSHLCEEL LKDKKHNVIG IDDFIGPTPF SLKLKNLKNL LPEKRFTFIK
     ENLLTADLAS LLEGVDVIFH LAAIPGVRSS WGNHFHPYAA HNIQALQRLL EACREHSIQT
     FVFASTSSVY GEKQGKVSEN TSLSPLSPYG VTKLTGEKLC HVYKQSFGIP IVILRFFTVY
     GPRQRPDMAF HRLIKQHLQQ KPLTIFGDGQ QSRDFTYISD CVKGITAVLG KPHLIGETVN
     IGGAERASVL KVVSLIEDIS GRKATLHFSD KIAGEPSNTW ADISKAKQLL HYDPATSLKD
     GLTNEIAYLS SLYQGE