YTFE_ECO27
ID YTFE_ECO27 Reviewed; 220 AA.
AC B7UQM4;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 25-MAY-2022, entry version 67.
DE RecName: Full=Iron-sulfur cluster repair protein YtfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN Name=ytfE {ECO:0000255|HAMAP-Rule:MF_01606}; OrderedLocusNames=E2348C_4540;
OS Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=574521;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E2348/69 / EPEC;
RX PubMed=18952797; DOI=10.1128/jb.01238-08;
RA Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R.,
RA Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A.,
RA Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G.;
RT "Complete genome sequence and comparative genome analysis of
RT enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL J. Bacteriol. 191:347-354(2009).
CC -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SIMILARITY: Belongs to the RIC family. YtfE subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01606}.
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DR EMBL; FM180568; CAS12088.1; -; Genomic_DNA.
DR RefSeq; WP_000331451.1; NC_011601.1.
DR AlphaFoldDB; B7UQM4; -.
DR SMR; B7UQM4; -.
DR EnsemblBacteria; CAS12088; CAS12088; E2348C_4540.
DR GeneID; 66510081; -.
DR KEGG; ecg:E2348C_4540; -.
DR HOGENOM; CLU_076075_2_0_6; -.
DR OMA; ACTTWRV; -.
DR Proteomes; UP000008205; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01606; RIC_YtfE; 1.
DR InterPro; IPR023742; FeS-repair_YftE.
DR InterPro; IPR012312; Hemerythrin-like.
DR InterPro; IPR019903; RIC_family.
DR PANTHER; PTHR36438; PTHR36438; 1.
DR Pfam; PF01814; Hemerythrin; 1.
DR Pfam; PF04405; ScdA_N; 1.
DR TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Iron; Metal-binding; Stress response.
FT CHAIN 1..220
FT /note="Iron-sulfur cluster repair protein YtfE"
FT /id="PRO_1000185839"
SQ SEQUENCE 220 AA; 24883 MW; D0F1B8CB1649880E CRC64;
MAYRDQPLGE LALSIPRASA LFRKYDMDYC CGGKQTLARA AARKELDVDV IEAELAKLAE
QPIEKDWRSA PLAEIIDHII VRYHDRHREQ LPELILQATK VERVHADKPS VPKGLTKYLT
MLHEELSSHM MKEEQILFPM IKQGMGSQAM GPISVMESEH DEAGELLEVI KHTTNNVTPP
PEACTTWKAM YNGINELIDD LMEHISLENN VLFPRALAGE