ID   YTFE_ECO45              Reviewed;         220 AA.
AC   B7MLM2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Iron-sulfur cluster repair protein YtfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN   Name=ytfE {ECO:0000255|HAMAP-Rule:MF_01606}; OrderedLocusNames=ECS88_4803;
OS   Escherichia coli O45:K1 (strain S88 / ExPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585035;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S88 / ExPEC;
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC       sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SIMILARITY: Belongs to the RIC family. YtfE subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
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DR   EMBL; CU928161; CAR05952.1; -; Genomic_DNA.
DR   RefSeq; WP_000331456.1; NC_011742.1.
DR   AlphaFoldDB; B7MLM2; -.
DR   SMR; B7MLM2; -.
DR   EnsemblBacteria; CAR05952; CAR05952; ECS88_4803.
DR   GeneID; 66671871; -.
DR   KEGG; ecz:ECS88_4803; -.
DR   HOGENOM; CLU_076075_2_0_6; -.
DR   OMA; ACTTWRV; -.
DR   Proteomes; UP000000747; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01606; RIC_YtfE; 1.
DR   InterPro; IPR023742; FeS-repair_YftE.
DR   InterPro; IPR012312; Hemerythrin-like.
DR   InterPro; IPR019903; RIC_family.
DR   PANTHER; PTHR36438; PTHR36438; 1.
DR   Pfam; PF01814; Hemerythrin; 1.
DR   Pfam; PF04405; ScdA_N; 1.
DR   TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Iron; Metal-binding; Stress response.
FT   CHAIN           1..220
FT                   /note="Iron-sulfur cluster repair protein YtfE"
FT                   /id="PRO_1000148172"
SQ   SEQUENCE   220 AA;  24883 MW;  CC81A560EDA6A03B CRC64;
     MAYRDQPLGE LALSIPRASA LFRKYDMDYC CGGKQTLARA AARKELDVEV IEAELAKLAE
     QPIEKDWRSA PLAEIIDHII VRYHDRHREQ LPELILQATK VERVHADKPS VPKGLTKYLT
     MLHEELSSHM MKEEQILFPM IKQGMGSQAM GPISVMESEH DEAGELLEVI KHTTNNVTPP
     PEACTTWKAM YNGINELIDD LMDHISLENN VLFPRALAGE