YTFE_ECO7I
ID YTFE_ECO7I Reviewed; 220 AA.
AC B7NUC3;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Iron-sulfur cluster repair protein YtfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN Name=ytfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN OrderedLocusNames=ECIAI39_4681;
OS Escherichia coli O7:K1 (strain IAI39 / ExPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=585057;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAI39 / ExPEC;
RX PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT "Organised genome dynamics in the Escherichia coli species results in
RT highly diverse adaptive paths.";
RL PLoS Genet. 5:E1000344-E1000344(2009).
CC -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SIMILARITY: Belongs to the RIC family. YtfE subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01606}.
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DR EMBL; CU928164; CAR20779.1; -; Genomic_DNA.
DR RefSeq; WP_000331451.1; NC_011750.1.
DR RefSeq; YP_002410542.1; NC_011750.1.
DR AlphaFoldDB; B7NUC3; -.
DR SMR; B7NUC3; -.
DR STRING; 585057.ECIAI39_4681; -.
DR EnsemblBacteria; CAR20779; CAR20779; ECIAI39_4681.
DR GeneID; 66510081; -.
DR KEGG; ect:ECIAI39_4681; -.
DR PATRIC; fig|585057.6.peg.4829; -.
DR HOGENOM; CLU_076075_2_0_6; -.
DR OMA; ACTTWRV; -.
DR Proteomes; UP000000749; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01606; RIC_YtfE; 1.
DR InterPro; IPR023742; FeS-repair_YftE.
DR InterPro; IPR012312; Hemerythrin-like.
DR InterPro; IPR019903; RIC_family.
DR PANTHER; PTHR36438; PTHR36438; 1.
DR Pfam; PF01814; Hemerythrin; 1.
DR Pfam; PF04405; ScdA_N; 1.
DR TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Iron; Metal-binding; Stress response.
FT CHAIN 1..220
FT /note="Iron-sulfur cluster repair protein YtfE"
FT /id="PRO_1000148174"
SQ SEQUENCE 220 AA; 24883 MW; D0F1B8CB1649880E CRC64;
MAYRDQPLGE LALSIPRASA LFRKYDMDYC CGGKQTLARA AARKELDVDV IEAELAKLAE
QPIEKDWRSA PLAEIIDHII VRYHDRHREQ LPELILQATK VERVHADKPS VPKGLTKYLT
MLHEELSSHM MKEEQILFPM IKQGMGSQAM GPISVMESEH DEAGELLEVI KHTTNNVTPP
PEACTTWKAM YNGINELIDD LMEHISLENN VLFPRALAGE