YTFE_ECOBW
ID YTFE_ECOBW Reviewed; 220 AA.
AC C4ZR85;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Iron-sulfur cluster repair protein YtfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN Name=ytfE {ECO:0000255|HAMAP-Rule:MF_01606}; OrderedLocusNames=BWG_3920;
OS Escherichia coli (strain K12 / MC4100 / BW2952).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=595496;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MC4100 / BW2952;
RX PubMed=19376874; DOI=10.1128/jb.00118-09;
RA Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R.,
RA Wang L.;
RT "Genomic sequencing reveals regulatory mutations and recombinational events
RT in the widely used MC4100 lineage of Escherichia coli K-12.";
RL J. Bacteriol. 191:4025-4029(2009).
CC -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01606}.
CC -!- SIMILARITY: Belongs to the RIC family. YtfE subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01606}.
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DR EMBL; CP001396; ACR65071.1; -; Genomic_DNA.
DR RefSeq; WP_000331456.1; NC_012759.1.
DR AlphaFoldDB; C4ZR85; -.
DR SMR; C4ZR85; -.
DR GeneID; 66671871; -.
DR KEGG; ebw:BWG_3920; -.
DR HOGENOM; CLU_076075_2_0_6; -.
DR OMA; ACTTWRV; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01606; RIC_YtfE; 1.
DR InterPro; IPR023742; FeS-repair_YftE.
DR InterPro; IPR012312; Hemerythrin-like.
DR InterPro; IPR019903; RIC_family.
DR PANTHER; PTHR36438; PTHR36438; 1.
DR Pfam; PF01814; Hemerythrin; 1.
DR Pfam; PF04405; ScdA_N; 1.
DR TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Iron; Metal-binding; Stress response.
FT CHAIN 1..220
FT /note="Iron-sulfur cluster repair protein YtfE"
FT /id="PRO_1000215699"
SQ SEQUENCE 220 AA; 24883 MW; CC81A560EDA6A03B CRC64;
MAYRDQPLGE LALSIPRASA LFRKYDMDYC CGGKQTLARA AARKELDVEV IEAELAKLAE
QPIEKDWRSA PLAEIIDHII VRYHDRHREQ LPELILQATK VERVHADKPS VPKGLTKYLT
MLHEELSSHM MKEEQILFPM IKQGMGSQAM GPISVMESEH DEAGELLEVI KHTTNNVTPP
PEACTTWKAM YNGINELIDD LMDHISLENN VLFPRALAGE