ID   YTFE_ECOSE              Reviewed;         220 AA.
AC   B6I2C2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Iron-sulfur cluster repair protein YtfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN   Name=ytfE {ECO:0000255|HAMAP-Rule:MF_01606}; OrderedLocusNames=ECSE_4515;
OS   Escherichia coli (strain SE11).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=409438;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SE11;
RX   PubMed=18931093; DOI=10.1093/dnares/dsn026;
RA   Oshima K., Toh H., Ogura Y., Sasamoto H., Morita H., Park S.-H., Ooka T.,
RA   Iyoda S., Taylor T.D., Hayashi T., Itoh K., Hattori M.;
RT   "Complete genome sequence and comparative analysis of the wild-type
RT   commensal Escherichia coli strain SE11 isolated from a healthy adult.";
RL   DNA Res. 15:375-386(2008).
CC   -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC       sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SIMILARITY: Belongs to the RIC family. YtfE subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
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DR   EMBL; AP009240; BAG80039.1; -; Genomic_DNA.
DR   RefSeq; WP_000331456.1; NC_011415.1.
DR   AlphaFoldDB; B6I2C2; -.
DR   SMR; B6I2C2; -.
DR   EnsemblBacteria; BAG80039; BAG80039; ECSE_4515.
DR   GeneID; 66671871; -.
DR   KEGG; ecy:ECSE_4515; -.
DR   HOGENOM; CLU_076075_2_0_6; -.
DR   OMA; ACTTWRV; -.
DR   Proteomes; UP000008199; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01606; RIC_YtfE; 1.
DR   InterPro; IPR023742; FeS-repair_YftE.
DR   InterPro; IPR012312; Hemerythrin-like.
DR   InterPro; IPR019903; RIC_family.
DR   PANTHER; PTHR36438; PTHR36438; 1.
DR   Pfam; PF01814; Hemerythrin; 1.
DR   Pfam; PF04405; ScdA_N; 1.
DR   TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Iron; Metal-binding; Stress response.
FT   CHAIN           1..220
FT                   /note="Iron-sulfur cluster repair protein YtfE"
FT                   /id="PRO_1000148178"
SQ   SEQUENCE   220 AA;  24883 MW;  CC81A560EDA6A03B CRC64;
     MAYRDQPLGE LALSIPRASA LFRKYDMDYC CGGKQTLARA AARKELDVEV IEAELAKLAE
     QPIEKDWRSA PLAEIIDHII VRYHDRHREQ LPELILQATK VERVHADKPS VPKGLTKYLT
     MLHEELSSHM MKEEQILFPM IKQGMGSQAM GPISVMESEH DEAGELLEVI KHTTNNVTPP
     PEACTTWKAM YNGINELIDD LMDHISLENN VLFPRALAGE