ID   YTFE_ECOSM              Reviewed;         220 AA.
AC   B1LR94;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Iron-sulfur cluster repair protein YtfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN   Name=ytfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN   OrderedLocusNames=EcSMS35_4688;
OS   Escherichia coli (strain SMS-3-5 / SECEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=439855;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SMS-3-5 / SECEC;
RX   PubMed=18708504; DOI=10.1128/jb.00661-08;
RA   Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C.,
RA   Ravel J., Stepanauskas R.;
RT   "Insights into the environmental resistance gene pool from the genome
RT   sequence of the multidrug-resistant environmental isolate Escherichia coli
RT   SMS-3-5.";
RL   J. Bacteriol. 190:6779-6794(2008).
CC   -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC       sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SIMILARITY: Belongs to the RIC family. YtfE subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
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DR   EMBL; CP000970; ACB16180.1; -; Genomic_DNA.
DR   RefSeq; WP_000331451.1; NC_010498.1.
DR   AlphaFoldDB; B1LR94; -.
DR   SMR; B1LR94; -.
DR   EnsemblBacteria; ACB16180; ACB16180; EcSMS35_4688.
DR   GeneID; 66510081; -.
DR   KEGG; ecm:EcSMS35_4688; -.
DR   HOGENOM; CLU_076075_2_0_6; -.
DR   OMA; ACTTWRV; -.
DR   Proteomes; UP000007011; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01606; RIC_YtfE; 1.
DR   InterPro; IPR023742; FeS-repair_YftE.
DR   InterPro; IPR012312; Hemerythrin-like.
DR   InterPro; IPR019903; RIC_family.
DR   PANTHER; PTHR36438; PTHR36438; 1.
DR   Pfam; PF01814; Hemerythrin; 1.
DR   Pfam; PF04405; ScdA_N; 1.
DR   TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Iron; Metal-binding; Stress response.
FT   CHAIN           1..220
FT                   /note="Iron-sulfur cluster repair protein YtfE"
FT                   /id="PRO_1000148179"
SQ   SEQUENCE   220 AA;  24883 MW;  D0F1B8CB1649880E CRC64;
     MAYRDQPLGE LALSIPRASA LFRKYDMDYC CGGKQTLARA AARKELDVDV IEAELAKLAE
     QPIEKDWRSA PLAEIIDHII VRYHDRHREQ LPELILQATK VERVHADKPS VPKGLTKYLT
     MLHEELSSHM MKEEQILFPM IKQGMGSQAM GPISVMESEH DEAGELLEVI KHTTNNVTPP
     PEACTTWKAM YNGINELIDD LMEHISLENN VLFPRALAGE