ID   YTFE_KLEP7              Reviewed;         220 AA.
AC   A6THB9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Iron-sulfur cluster repair protein YtfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN   Name=ytfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN   OrderedLocusNames=KPN78578_45290; ORFNames=KPN_04602;
OS   Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=272620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578;
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC       sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SIMILARITY: Belongs to the RIC family. YtfE subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
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DR   EMBL; CP000647; ABR79953.1; -; Genomic_DNA.
DR   RefSeq; WP_004152016.1; NC_009648.1.
DR   AlphaFoldDB; A6THB9; -.
DR   SMR; A6THB9; -.
DR   STRING; 272620.KPN_04602; -.
DR   EnsemblBacteria; ABR79953; ABR79953; KPN_04602.
DR   KEGG; kpn:KPN_04602; -.
DR   HOGENOM; CLU_076075_2_0_6; -.
DR   OMA; ACTTWRV; -.
DR   Proteomes; UP000000265; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01606; RIC_YtfE; 1.
DR   InterPro; IPR023742; FeS-repair_YftE.
DR   InterPro; IPR012312; Hemerythrin-like.
DR   InterPro; IPR019903; RIC_family.
DR   PANTHER; PTHR36438; PTHR36438; 1.
DR   Pfam; PF01814; Hemerythrin; 1.
DR   Pfam; PF04405; ScdA_N; 1.
DR   TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Iron; Metal-binding; Reference proteome; Stress response.
FT   CHAIN           1..220
FT                   /note="Iron-sulfur cluster repair protein YtfE"
FT                   /id="PRO_1000069420"
SQ   SEQUENCE   220 AA;  24739 MW;  BE771C1C2A43D4C5 CRC64;
     MAFRDQPLGE LALTIPRASA LFRQYDMDYC CGGKQTLARA ASRKALDVAV IEAELAKLAE
     QPLSRDWRAA PLAEIIDHII VRYHDRHREQ LPELILQATK VERVHADKPN VPKGLTKYLT
     MLHQELSSHM MKEEQILFPM IKQGMGAQAG GPISVMESEH DEAGELLEVI KHITHNVTPP
     PEACTTWKAM YNGINEMIDD LMEHISLENN VLFPRALGGK