ID   YTFE_SALG2              Reviewed;         220 AA.
AC   B5R9F8;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   04-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Iron-sulfur cluster repair protein YtfE {ECO:0000255|HAMAP-Rule:MF_01606};
GN   Name=ytfE {ECO:0000255|HAMAP-Rule:MF_01606}; OrderedLocusNames=SG4243;
OS   Salmonella gallinarum (strain 287/91 / NCTC 13346).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=550538;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=287/91 / NCTC 13346;
RX   PubMed=18583645; DOI=10.1101/gr.077404.108;
RA   Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S.,
RA   Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M., Barron A.,
RA   Layton A., Pickard D., Kingsley R.A., Bignell A., Clark L., Harris B.,
RA   Ormond D., Abdellah Z., Brooks K., Cherevach I., Chillingworth T.,
RA   Woodward J., Norberczak H., Lord A., Arrowsmith C., Jagels K., Moule S.,
RA   Mungall K., Saunders M., Whitehead S., Chabalgoity J.A., Maskell D.,
RA   Humphreys T., Roberts M., Barrow P.A., Dougan G., Parkhill J.;
RT   "Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella
RT   gallinarum 287/91 provides insights into evolutionary and host adaptation
RT   pathways.";
RL   Genome Res. 18:1624-1637(2008).
CC   -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC       sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01606}.
CC   -!- SIMILARITY: Belongs to the RIC family. YtfE subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01606}.
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DR   EMBL; AM933173; CAR40006.1; -; Genomic_DNA.
DR   RefSeq; WP_000331471.1; NC_011274.1.
DR   AlphaFoldDB; B5R9F8; -.
DR   SMR; B5R9F8; -.
DR   EnsemblBacteria; CAR40006; CAR40006; SG4243.
DR   KEGG; seg:SG4243; -.
DR   HOGENOM; CLU_076075_2_0_6; -.
DR   OMA; ACTTWRV; -.
DR   Proteomes; UP000008321; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01606; RIC_YtfE; 1.
DR   InterPro; IPR023742; FeS-repair_YftE.
DR   InterPro; IPR012312; Hemerythrin-like.
DR   InterPro; IPR019903; RIC_family.
DR   PANTHER; PTHR36438; PTHR36438; 1.
DR   Pfam; PF01814; Hemerythrin; 1.
DR   Pfam; PF04405; ScdA_N; 1.
DR   TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Iron; Metal-binding; Stress response.
FT   CHAIN           1..220
FT                   /note="Iron-sulfur cluster repair protein YtfE"
FT                   /id="PRO_1000148185"
SQ   SEQUENCE   220 AA;  24911 MW;  5FA4D10F0E35C5F5 CRC64;
     MAYRDQPLGE LALSIPRASA LFRQYDMDYC CGGKQTLARA AARHDVDIDI IEAQLAQLAE
     QPIEKDWRAV PLADIIDHIV VRYHDRHREQ LPELILQATK VERVHADKPN VPRGLTKYLT
     ALHEELSSHM MKEEQILFPM IKQGMGRQAT GPISVMESEH DEAGELVDVI KHVTQNVTPP
     PEACTTWKAM YNGINEMIDD LMEHISLENN VLFPRALAGE