ID   YTKK_BACSU              Reviewed;         255 AA.
AC   O34308; Q795U3;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Putative oxidoreductase YtkK;
DE            EC=1.-.-.-;
GN   Name=ytkK; OrderedLocusNames=BSU29420;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9387221; DOI=10.1099/00221287-143-11-3431;
RA   Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.;
RT   "Sequencing and functional annotation of the Bacillus subtilis genes in the
RT   200 kb rrnB-dnaB region.";
RL   Microbiology 143:3431-3441(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
CC   -!- CAUTION: Phe-155 is present instead of the conserved Tyr which is
CC       expected to be an active site residue. {ECO:0000305}.
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DR   EMBL; AF008220; AAC00322.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB14902.1; -; Genomic_DNA.
DR   PIR; F69994; F69994.
DR   RefSeq; NP_390820.1; NC_000964.3.
DR   RefSeq; WP_004398521.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O34308; -.
DR   SMR; O34308; -.
DR   STRING; 224308.BSU29420; -.
DR   PaxDb; O34308; -.
DR   EnsemblBacteria; CAB14902; CAB14902; BSU_29420.
DR   GeneID; 937351; -.
DR   KEGG; bsu:BSU29420; -.
DR   PATRIC; fig|224308.43.peg.3080; -.
DR   eggNOG; COG1028; Bacteria.
DR   InParanoid; O34308; -.
DR   OMA; MGEATCH; -.
DR   PhylomeDB; O34308; -.
DR   BioCyc; BSUB:BSU29420-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR   GO; GO:0030497; P:fatty acid elongation; IBA:GO_Central.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..255
FT                   /note="Putative oxidoreductase YtkK"
FT                   /id="PRO_0000377000"
FT   BINDING         7..14
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   255 AA;  27974 MW;  D1D940C83895B83A CRC64;
     MRHALITAGS KGLGRKVTET LLAKGYSVTV NYRQDEEAVS RLKEACPDCL DRLQFVKGDV
     TKKEDLLRIA EAALNRFGRI DFLINNAGPY IFERKKLADY TDDEWYGMLE GNLSAVFHLF
     KAVIPIMRKQ QFGRIITYGF QGAAHAPGWL HRSAFGAAKV GLASLTKTIA IEEAEFGITA
     NMVCPGDIVG DMKEASIEEA RMRIGKEKTP IGRSGTGEDI ARIIAFLCEE NSDLVTGTVI
     EATGGLNVIN KNQTT