YTP1_YEAST
ID YTP1_YEAST Reviewed; 459 AA.
AC P53584; D6W0V6;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Protein YTP1;
GN Name=YTP1; OrderedLocusNames=YNL237W; ORFNames=N1129;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=YM256;
RA West R.W. Jr., Ma J.L., Thomas S.;
RL Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8896273;
RX DOI=10.1002/(sici)1097-0061(199609)12:10b<1071::aid-yea4>3.0.co;2-s;
RA Pandolfo D., de Antoni A., Lanfranchi G., Valle G.;
RT "The DNA sequence of cosmid 14-5 from chromosome XIV reveals 21 open
RT reading frames including a novel gene encoding a globin-like domain.";
RL Yeast 12:1071-1076(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169873;
RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K.,
RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K.,
RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M.,
RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F.,
RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F.,
RA Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C.,
RA Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A.,
RA Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H.,
RA Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L.,
RA Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R.,
RA Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D.,
RA Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A.,
RA Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C.,
RA Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F.,
RA Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G.,
RA Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M.,
RA Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
RT evolutionary implications.";
RL Nature 387:93-98(1997).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [5]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 208353 / W303-1A;
RX PubMed=16847258; DOI=10.1073/pnas.0604075103;
RA Kim H., Melen K., Oesterberg M., von Heijne G.;
RT "A global topology map of the Saccharomyces cerevisiae membrane proteome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006).
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
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DR EMBL; U22109; AAB06186.1; -; Genomic_DNA.
DR EMBL; Z71513; CAA96142.1; -; Genomic_DNA.
DR EMBL; Z69381; CAA93361.1; -; Genomic_DNA.
DR EMBL; BK006947; DAA10322.1; -; Genomic_DNA.
DR PIR; S59812; S59812.
DR RefSeq; NP_014162.1; NM_001183075.1.
DR AlphaFoldDB; P53584; -.
DR BioGRID; 35602; 33.
DR DIP; DIP-4563N; -.
DR IntAct; P53584; 2.
DR STRING; 4932.YNL237W; -.
DR MoonDB; P53584; Predicted.
DR TCDB; 9.B.57.1.2; the conidiation and conidial germination protein (ccgp) family.
DR PaxDb; P53584; -.
DR PRIDE; P53584; -.
DR EnsemblFungi; YNL237W_mRNA; YNL237W; YNL237W.
DR GeneID; 855484; -.
DR KEGG; sce:YNL237W; -.
DR SGD; S000005181; YTP1.
DR VEuPathDB; FungiDB:YNL237W; -.
DR eggNOG; ENOG502QRB1; Eukaryota.
DR GeneTree; ENSGT00940000176688; -.
DR HOGENOM; CLU_034579_1_0_1; -.
DR InParanoid; P53584; -.
DR OMA; DYQHTAM; -.
DR BioCyc; YEAST:G3O-33236-MON; -.
DR PRO; PR:P53584; -.
DR Proteomes; UP000002311; Chromosome XIV.
DR RNAct; P53584; protein.
DR GO; GO:0016021; C:integral component of membrane; ISM:SGD.
DR InterPro; IPR018827; Uncharacterised_YCR061W_C.
DR Pfam; PF10355; Ytp1; 1.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..459
FT /note="Protein YTP1"
FT /id="PRO_0000066529"
FT TOPO_DOM 1..6
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 28..59
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 81..82
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 104..122
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 144..170
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 192..205
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 227..266
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 267..287
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 288..295
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 317..322
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 344..351
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 373..389
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 390..410
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 411..459
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 459 AA; 51644 MW; 7175F063044D2233 CRC64;
MTAANKNIVF GFSRSISAIL LICFFFEKVC GDMEHDMGMD DTSGYTRPEI VQAGSKSFHW
LCTLGFLLLL PSVVTCLSFA GRIYSATLLQ CTCAVYAFLE AAVLRFQDND GVENRTSRGT
AWFLVGLTWI TLFFGGLAGG TGFLVKSKRL QTFISNAGEK RLSYIHRGLS FLTVLTGWVK
VCLAPVALFG FCREAHTGQC IAHGIMGSAF VLYGFIYVLV LVIPWIRSAQ TSYSQDYVDS
WVMCIWGVVN TFTEHRWGRE GWSVHDYQHT FMGIIWWTGG ILGIFLSRNG RRTFVPSLII
IFTGWAMSEH AQHLIISTKV HNMFGLVLMC GGALRIIEIS FLLRDKRTLD KIHSFQYLAP
FCLVCSGLLF MGANEEQLIL VLRLGGDHSA YVLIIVSGAF LVYFWMIACL EFYLYLLEKG
KQGFLPKSYE LEEENNNVSF ELDNISNEDV DEDTTPFNV
