ID   YTRA_BACSU              Reviewed;         130 AA.
AC   O34712; Q795Q0;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=HTH-type transcriptional repressor YtrA;
GN   Name=ytrA; OrderedLocusNames=BSU30460;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9387221; DOI=10.1099/00221287-143-11-3431;
RA   Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.;
RT   "Sequencing and functional annotation of the Bacillus subtilis genes in the
RT   200 kb rrnB-dnaB region.";
RL   Microbiology 143:3431-3441(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   FUNCTION, AND DEVELOPMENTAL STAGE.
RX   PubMed=10986249; DOI=10.1128/jb.182.19.5454-5461.2000;
RA   Yoshida K., Fujita Y., Ehrlich S.D.;
RT   "An operon for a putative ATP-binding cassette transport system involved in
RT   acetoin utilization of Bacillus subtilis.";
RL   J. Bacteriol. 182:5454-5461(2000).
CC   -!- FUNCTION: Negatively regulates ABC transporter complex ytrBCDEF that
CC       plays a role in acetoin utilization during stationary phase and
CC       sporulation. {ECO:0000269|PubMed:10986249}.
CC   -!- DEVELOPMENTAL STAGE: Expressed early in the stationary phase.
CC       {ECO:0000269|PubMed:10986249}.
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DR   EMBL; AF008220; AAC00247.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15024.1; -; Genomic_DNA.
DR   PIR; G69999; G69999.
DR   RefSeq; NP_390924.1; NC_000964.3.
DR   RefSeq; WP_003229121.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O34712; -.
DR   SMR; O34712; -.
DR   STRING; 224308.BSU30460; -.
DR   PaxDb; O34712; -.
DR   PRIDE; O34712; -.
DR   EnsemblBacteria; CAB15024; CAB15024; BSU_30460.
DR   GeneID; 937244; -.
DR   KEGG; bsu:BSU30460; -.
DR   PATRIC; fig|224308.179.peg.3303; -.
DR   eggNOG; COG1725; Bacteria.
DR   InParanoid; O34712; -.
DR   OMA; ERDGWIY; -.
DR   PhylomeDB; O34712; -.
DR   BioCyc; BSUB:BSU30460-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..130
FT                   /note="HTH-type transcriptional repressor YtrA"
FT                   /id="PRO_0000360730"
FT   DOMAIN          10..78
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        38..57
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
SQ   SEQUENCE   130 AA;  14694 MW;  16464E57E99871A9 CRC64;
     MIQIDPRSST PIYEQIIQQM KELCLKGIMK PGDKLPSVRE LATIIIANPN TVSKAYKELE
     REGIIETLRG RGTYISENAK TTLVEGKMTM IKEQLKQLII DAHYAGVELE KLHEWIKEIS
     ADVKGGKKND