YTRB_BACSU
ID YTRB_BACSU Reviewed; 292 AA.
AC O34641; Q795Q1;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=ABC transporter ATP-binding protein YtrB;
GN Name=ytrB; OrderedLocusNames=BSU30450;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9387221; DOI=10.1099/00221287-143-11-3431;
RA Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.;
RT "Sequencing and functional annotation of the Bacillus subtilis genes in the
RT 200 kb rrnB-dnaB region.";
RL Microbiology 143:3431-3441(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP FUNCTION, DEVELOPMENTAL STAGE, AND INDUCTION.
RX PubMed=10986249; DOI=10.1128/jb.182.19.5454-5461.2000;
RA Yoshida K., Fujita Y., Ehrlich S.D.;
RT "An operon for a putative ATP-binding cassette transport system involved in
RT acetoin utilization of Bacillus subtilis.";
RL J. Bacteriol. 182:5454-5461(2000).
CC -!- FUNCTION: Part of the ABC transporter complex YtrBCDEF that plays a
CC role in acetoin utilization during stationary phase and sporulation.
CC {ECO:0000269|PubMed:10986249}.
CC -!- SUBUNIT: The complex is composed of 2 ATP-binding proteins (YtrB and
CC YtrE), 2 transmembrane proteins (YtrC and YtrD) and a solute-binding
CC protein (YtrF). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Peripheral membrane
CC protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Expressed early in the stationary phase.
CC {ECO:0000269|PubMed:10986249}.
CC -!- INDUCTION: Negatively regulated by YtrA. {ECO:0000269|PubMed:10986249}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; AF008220; AAC00248.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB15023.1; -; Genomic_DNA.
DR PIR; H69999; H69999.
DR RefSeq; NP_390923.1; NC_000964.3.
DR RefSeq; WP_004398506.1; NZ_JNCM01000036.1.
DR AlphaFoldDB; O34641; -.
DR SMR; O34641; -.
DR STRING; 224308.BSU30450; -.
DR TCDB; 3.A.1.153.1; the atp-binding cassette (abc) superfamily.
DR PaxDb; O34641; -.
DR PRIDE; O34641; -.
DR EnsemblBacteria; CAB15023; CAB15023; BSU_30450.
DR GeneID; 936641; -.
DR KEGG; bsu:BSU30450; -.
DR PATRIC; fig|224308.179.peg.3302; -.
DR eggNOG; COG1131; Bacteria.
DR InParanoid; O34641; -.
DR OMA; EDIERMC; -.
DR PhylomeDB; O34641; -.
DR BioCyc; BSUB:BSU30450-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW Reference proteome; Transport.
FT CHAIN 1..292
FT /note="ABC transporter ATP-binding protein YtrB"
FT /id="PRO_0000360813"
FT DOMAIN 2..227
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 34..41
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 292 AA; 33819 MW; 3514BA7BCE2CCF17 CRC64;
MIELRQLSKA IDGNQVLKDV SLTIEKGEIF GLLGRNGSGK TTMLRLIQQI IFADSGTILF
DGVEIKKHPK VKQNIIYMPV QNPFYDKYTY KQLVDILRRI YPKFDVTYAN ELMNRYEIPE
TKKYRELSTG LKKQLSLVLS FAARPALILL DEPTDGIDAV TRHDVLQLMV DEVAERDTSI
LITSHRLEDI ERMCNRIGFL EDNSLTNVMD LDELKEEYIK IQMAFDTDVN LAIREQNIPM
LDQAGVFYTV LIPKSDEEKK SFLRELKPKV WNELPVNLEE VFIAKFGGKR RW
