ID   YTRF_BACSU              Reviewed;         436 AA.
AC   O35005; Q795Q4;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=ABC transporter permease YtrF;
DE   Flags: Precursor;
GN   Name=ytrF; OrderedLocusNames=BSU30410;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9387221; DOI=10.1099/00221287-143-11-3431;
RA   Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.;
RT   "Sequencing and functional annotation of the Bacillus subtilis genes in the
RT   200 kb rrnB-dnaB region.";
RL   Microbiology 143:3431-3441(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   FUNCTION, DEVELOPMENTAL STAGE, AND INDUCTION.
RX   PubMed=10986249; DOI=10.1128/jb.182.19.5454-5461.2000;
RA   Yoshida K., Fujita Y., Ehrlich S.D.;
RT   "An operon for a putative ATP-binding cassette transport system involved in
RT   acetoin utilization of Bacillus subtilis.";
RL   J. Bacteriol. 182:5454-5461(2000).
CC   -!- FUNCTION: Part of the ABC transporter complex YtrBCDEF that plays a
CC       role in acetoin utilization during stationary phase and sporulation.
CC       {ECO:0000269|PubMed:10986249}.
CC   -!- SUBUNIT: The complex is composed of 2 ATP-binding proteins (YtrB and
CC       YtrE), 2 transmembrane proteins (YtrC and YtrD) and a solute-binding
CC       protein (YtrF). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC       Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed early in the stationary phase.
CC       {ECO:0000269|PubMed:10986249}.
CC   -!- INDUCTION: Negatively regulated by YtrA. {ECO:0000269|PubMed:10986249}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF008220; AAC00252.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15019.1; -; Genomic_DNA.
DR   PIR; D70000; D70000.
DR   RefSeq; NP_390919.1; NC_000964.3.
DR   RefSeq; WP_004398682.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O35005; -.
DR   SMR; O35005; -.
DR   STRING; 224308.BSU30410; -.
DR   TCDB; 3.A.1.122.19; the atp-binding cassette (abc) superfamily.
DR   PaxDb; O35005; -.
DR   PRIDE; O35005; -.
DR   EnsemblBacteria; CAB15019; CAB15019; BSU_30410.
DR   GeneID; 937247; -.
DR   KEGG; bsu:BSU30410; -.
DR   PATRIC; fig|224308.179.peg.3298; -.
DR   eggNOG; COG0577; Bacteria.
DR   OMA; IGIFNTM; -.
DR   PhylomeDB; O35005; -.
DR   BioCyc; BSUB:BSU30410-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   InterPro; IPR003838; ABC3_permease_dom.
DR   InterPro; IPR025857; MacB_PCD.
DR   Pfam; PF02687; FtsX; 1.
DR   Pfam; PF12704; MacB_PCD; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Coiled coil; Lipoprotein; Membrane; Palmitate;
KW   Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           32..436
FT                   /note="ABC transporter permease YtrF"
FT                   /id="PRO_0000360764"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        350..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        396..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   COILED          115..165
FT                   /evidence="ECO:0000255"
FT   LIPID           32
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           32
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   436 AA;  48421 MW;  4446127C4CBE7BDD CRC64;
     MRFKDQVHFI RRNMKKNRLR VFMTILATTM ACAFLVVLSS VGFGIQKTIT DMTMSQQIVT
     KVSVMGKEGD KPIKKADLEK YDHVRSVVER TQVYEPNKAT LGNRTNESSN LIFTNMNDEL
     KANMELEKGR VAKSENEIVV GYDFAKRLLT KKESEEYNKK IEEAKGNPED IKEPKGYTKD
     ILNKTIELSV SKTDSKTGDV TKTKTYDFKI VGITKKPSQD WMEDSNIFIS DQFKKDFSEF
     LDFKGGNVET NIGVFADKFE NVEQLTNDLT DDGYYVTSVT TELEGANTFF MVFKIGLIFV
     GCIAVIISAI GIFNTMTMAV TERTQEIGIM KAIGASPSII RRMFLMESAY IGILGCVIGI
     IISYGVSYLV NLAVPMILAA TSGGDAGDLN YTFSYIPASL VIIAVVICGG VAVISGMNPA
     RKATKTNVLT ALRREL