ID   YTX2_XENLA              Reviewed;        1308 AA.
AC   P14381;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Transposon TX1 uncharacterized 149 kDa protein;
DE   AltName: Full=ORF 2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2550791; DOI=10.1128/mcb.9.7.3018-3027.1989;
RA   Garrett J.E., Knutzon D.S., Carroll D.;
RT   "Composite transposable elements in the Xenopus laevis genome.";
RL   Mol. Cell. Biol. 9:3018-3027(1989).
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DR   EMBL; M26915; AAA49976.1; -; Genomic_DNA.
DR   PIR; B32494; B32494.
DR   AlphaFoldDB; P14381; -.
DR   SMR; P14381; -.
DR   PRIDE; P14381; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.60.10.10; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR000477; RT_dom.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56219; SSF56219; 1.
DR   SUPFAM; SSF56672; SSF56672; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome; Transposable element.
FT   CHAIN           1..1308
FT                   /note="Transposon TX1 uncharacterized 149 kDa protein"
FT                   /id="PRO_0000066537"
FT   DOMAIN          494..765
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00405"
SQ   SEQUENCE   1308 AA;  149578 MW;  C9A9C98CDC169C19 CRC64;
     MALSISTLNT NGCRNPFRMF QVLSFLRQGG YSVSFLQETH TTPELEASWN LEWKGRVFFN
     HLTWTSCGVV TLFSDSFQPE VLSATSVIPG RLLHLRVRES GRTYNLMNVY APTTGPERAR
     FFESLSAYME TIDSDEALII GGDFNYTLDA RDRNVPKKRD SSESVLRELI AHFSLVDVWR
     EQNPETVAFT YVRVRDGHVS QSRIDRIYIS SHLMSRAQSS TIRLAPFSDH NCVSLRMSIA
     PSLPKAAYWH FNNSLLEDEG FAKSVRDTWR GWRAFQDEFA TLNQWWDVGK VHLKLLCQEY
     TKSVSGQRNA EIEALNGEVL DLEQRLSGSE DQALQCEYLE RKEALRNMEQ RQARGAFVRS
     RMQLLCDMDR GSRFFYALEK KKGNRKQITC LFAEDGTPLE DPEAIRDRAR SFYQNLFSPD
     PISPDACEEL WDGLPVVSER RKERLETPIT LDELSQALRL MPHNKSPGLD GLTIEFFQFF
     WDTLGPDFHR VLTEAFKKGE LPLSCRRAVL SLLPKKGDLR LIKNWRPVSL LSTDYKIVAK
     AISLRLKSVL AEVIHPDQSY TVPGRTIFDN VFLIRDLLHF ARRTGLSLAF LSLDQEKAFD
     RVDHQYLIGT LQAYSFGPQF VGYLKTMYAS AECLVKINWS LTAPLAFGRG VRQGCPLSGQ
     LYSLAIEPFL CLLRKRLTGL VLKEPDMRVV LSAYADDVIL VAQDLVDLER AQECQEVYAA
     ASSARINWSK SSGLLEGSLK VDFLPPAFRD ISWESKIIKY LGVYLSAEEY PVSQNFIELE
     ECVLTRLGKW KGFAKVLSMR GRALVINQLV ASQIWYRLIC LSPTQEFIAK IQRRLLDFLW
     IGKHWVSAGV SSLPLKEGGQ GVVCIRSQVH TFRLQQIQRY LYADPSPQWC TLASSFYRQV
     RNMGYDRQLF IIEPEGFLRN LSTLPAYYQD TLKTWSMVSV LRQGATEGED ILNEPLLYNP
     SFKTRMLESI SIRRRLCQAQ LTRVGDLLDF EKSDWVDSQA VMQRMGFLTT RVPHRLLKEI
     KDTISPDSHT FIDGVLHAGE PRPPWNSSPP DIIIAPKTRQ SPQAPPSPNL SQLENFPLTR
     FHDITRKLLY SLMLHTVHFL ALISRYDTIW RRVLNEGERP QWRAFYSSLV PRPTGDLSWK
     VLHGALSTGE YLARFTDSPA ACPFCGKGES VFHAYFTCAR LQPLLALLRK LYLQFWLHFS
     PHVYIFGRPV SRDNKEKDLL SNLLLALAKL VIHKSRKQCL EGGNPLPAEV LFRVLVRSRI
     RAEYTQAVFT GRLKEFADQW AIDGVLCSVS PDLVSVQTIL TLPYLSAL