ID   YU87_ARATH              Reviewed;         410 AA.
AC   O80832;
DT   21-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=UPF0187 protein At2g45870, chloroplastic;
DE   Flags: Precursor;
GN   OrderedLocusNames=At2g45870; ORFNames=F4I18.15;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0187 family. {ECO:0000305}.
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DR   EMBL; AC004665; AAC28537.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC10612.1; -; Genomic_DNA.
DR   EMBL; AY074634; AAL69450.1; -; mRNA.
DR   PIR; T02460; T02460.
DR   RefSeq; NP_182111.1; NM_130150.3.
DR   AlphaFoldDB; O80832; -.
DR   SMR; O80832; -.
DR   BioGRID; 4531; 3.
DR   IntAct; O80832; 3.
DR   STRING; 3702.AT2G45870.1; -.
DR   PaxDb; O80832; -.
DR   PRIDE; O80832; -.
DR   ProteomicsDB; 242970; -.
DR   EnsemblPlants; AT2G45870.1; AT2G45870.1; AT2G45870.
DR   GeneID; 819195; -.
DR   Gramene; AT2G45870.1; AT2G45870.1; AT2G45870.
DR   KEGG; ath:AT2G45870; -.
DR   Araport; AT2G45870; -.
DR   TAIR; locus:2050740; AT2G45870.
DR   eggNOG; ENOG502QSQE; Eukaryota.
DR   HOGENOM; CLU_029790_7_0_1; -.
DR   InParanoid; O80832; -.
DR   OMA; EIVSWAG; -.
DR   OrthoDB; 1544046at2759; -.
DR   PhylomeDB; O80832; -.
DR   PRO; PR:O80832; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O80832; baseline and differential.
DR   Genevisible; O80832; AT.
DR   GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042651; C:thylakoid membrane; IDA:TAIR.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:0042548; P:regulation of photosynthesis, light reaction; IDA:TAIR.
DR   InterPro; IPR024701; At3g61320-like.
DR   InterPro; IPR021134; Bestrophin/UPF0187.
DR   InterPro; IPR044669; UPF0187.
DR   PANTHER; PTHR33281; PTHR33281; 1.
DR   Pfam; PF01062; Bestrophin; 1.
DR   PIRSF; PIRSF016988; UCP016988; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Membrane; Plastid; Reference proteome; Transit peptide;
KW   Transmembrane; Transmembrane helix.
FT   TRANSIT         1..?
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..410
FT                   /note="UPF0187 protein At2g45870, chloroplastic"
FT                   /id="PRO_0000036236"
FT   TRANSMEM        111..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        337..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   410 AA;  46280 MW;  FD5E541A36850BED CRC64;
     MYQSMNLSFS SNFTNLSFLK PRLYSGISAR APKSLHFKFN PSCVSSGPKS DDSPLSEKLI
     SLLKAVPNWS DGIKERRMQQ KRSLYTHENW VRHRSSLRHL RHVSSSPSSR VILSLIPPVF
     FFTTVAILIA GYNSAVDLDW LPDFFPVLRA SPLPYQLTAP ALALLLVFRT EASYSRFEQG
     RKAWVKIISG TNDLARLVIS SVHGSGDELI IRDALLRYIV AFPVALKCHV IYGSDIASDL
     KNVIEVDDLS LILQSKHRPR CVIQFISQSL QLLNLDSTKI DMLETKMMQL QEGIGVCEQL
     MGIPIPLSYT RLTSRFLVLW HLTLPVILWD DCHWNVVPAT FISAASLFCI EEVGVLIEEP
     FSMLALDELC AMVLSNSDEA VESKEVIRNR IIAKKRILEI KHSSNGWHKS