ID   CBY3_HUMAN              Reviewed;         242 AA.
AC   A6NI87;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 3.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Protein chibby homolog 3;
GN   Name=CBY3;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA   Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA   Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA   Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA   Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA   Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA   Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
CC   -!- MISCELLANEOUS: 'Chibby' is Japanese for 'small'; the gene was so named
CC       for the RNAi phenotype seen in flies.
CC   -!- SIMILARITY: Belongs to the chibby family. {ECO:0000305}.
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DR   EMBL; AC136604; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS47354.1; -.
DR   RefSeq; NP_001157916.1; NM_001164444.1.
DR   AlphaFoldDB; A6NI87; -.
DR   STRING; 9606.ENSP00000366173; -.
DR   iPTMnet; A6NI87; -.
DR   PhosphoSitePlus; A6NI87; -.
DR   BioMuta; CBY3; -.
DR   MassIVE; A6NI87; -.
DR   PaxDb; A6NI87; -.
DR   PeptideAtlas; A6NI87; -.
DR   PRIDE; A6NI87; -.
DR   ProteomicsDB; 1257; -.
DR   Antibodypedia; 59234; 8 antibodies from 7 providers.
DR   DNASU; 646019; -.
DR   Ensembl; ENST00000376974.5; ENSP00000366173.4; ENSG00000204659.5.
DR   Ensembl; ENST00000639980.2; ENSP00000491827.1; ENSG00000283718.2.
DR   GeneID; 646019; -.
DR   KEGG; hsa:646019; -.
DR   MANE-Select; ENST00000376974.5; ENSP00000366173.4; NM_001164444.2; NP_001157916.1.
DR   UCSC; uc021yjf.2; human.
DR   CTD; 646019; -.
DR   GeneCards; CBY3; -.
DR   HGNC; HGNC:33278; CBY3.
DR   HPA; ENSG00000204659; Tissue enriched (testis).
DR   neXtProt; NX_A6NI87; -.
DR   PharmGKB; PA162381185; -.
DR   VEuPathDB; HostDB:ENSG00000204659; -.
DR   eggNOG; KOG4119; Eukaryota.
DR   GeneTree; ENSGT00940000153137; -.
DR   HOGENOM; CLU_1227257_0_0_1; -.
DR   InParanoid; A6NI87; -.
DR   OMA; PSSCVPY; -.
DR   OrthoDB; 1542409at2759; -.
DR   PhylomeDB; A6NI87; -.
DR   TreeFam; TF324419; -.
DR   PathwayCommons; A6NI87; -.
DR   SignaLink; A6NI87; -.
DR   BioGRID-ORCS; 646019; 8 hits in 1060 CRISPR screens.
DR   GenomeRNAi; 646019; -.
DR   Pharos; A6NI87; Tdark.
DR   PRO; PR:A6NI87; -.
DR   Proteomes; UP000005640; Chromosome 5.
DR   RNAct; A6NI87; protein.
DR   Bgee; ENSG00000204659; Expressed in right testis and 88 other tissues.
DR   CDD; cd07429; Cby_like; 1.
DR   InterPro; IPR028118; Chibby_fam.
DR   Pfam; PF14645; Chibby; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..242
FT                   /note="Protein chibby homolog 3"
FT                   /id="PRO_0000340100"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   242 AA;  27343 MW;  C2236C4C27CBEAC3 CRC64;
     MWASRDHLPE PDLGDAAPPG SPSSFWTSGL PRQERSTSRQ RSRGSPSSTC VPYKVHALAT
     FECSATSHAS RLWQTLQQFW ADHISRPFSP RRPPLRRMPS LSTFYLLDHN TRQAELGLAY
     GAPCMRLSNQ AFVFRGGRWT TESQLARTRS PLLSRTAWGW KAQVQRSKSQ VLLEENNYLK
     LQQELLIDML TETMARMHLL EKQRNPEVIP TAAARAGQRK MRKRAGASAG VLMIQPCALD
     SQ