CBY3_MOUSE
ID CBY3_MOUSE Reviewed; 235 AA.
AC Q9CVN6; Q5NCA8;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Protein chibby homolog 3;
GN Name=Cby3;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 10-235.
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- MISCELLANEOUS: 'Chibby' is Japanese for 'small'; the gene was so named
CC for the RNAi phenotype seen in flies.
CC -!- SIMILARITY: Belongs to the chibby family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAI23999.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL645904; CAI23999.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK007228; BAB24904.1; -; mRNA.
DR AlphaFoldDB; Q9CVN6; -.
DR SMR; Q9CVN6; -.
DR STRING; 10090.ENSMUSP00000131004; -.
DR PhosphoSitePlus; Q9CVN6; -.
DR PaxDb; Q9CVN6; -.
DR PRIDE; Q9CVN6; -.
DR ProteomicsDB; 265573; -.
DR Antibodypedia; 59234; 8 antibodies from 7 providers.
DR Ensembl; ENSMUST00000164067; ENSMUSP00000131004; ENSMUSG00000050087.
DR UCSC; uc007isi.1; mouse.
DR MGI; MGI:1923903; Cby3.
DR VEuPathDB; HostDB:ENSMUSG00000050087; -.
DR eggNOG; KOG4119; Eukaryota.
DR GeneTree; ENSGT00940000153137; -.
DR HOGENOM; CLU_1227257_0_0_1; -.
DR InParanoid; Q9CVN6; -.
DR OMA; PSSCVPY; -.
DR PhylomeDB; Q9CVN6; -.
DR TreeFam; TF324419; -.
DR PRO; PR:Q9CVN6; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q9CVN6; protein.
DR Bgee; ENSMUSG00000050087; Expressed in seminiferous tubule of testis and 15 other tissues.
DR ExpressionAtlas; Q9CVN6; baseline and differential.
DR Genevisible; Q9CVN6; MM.
DR CDD; cd07429; Cby_like; 1.
DR InterPro; IPR028118; Chibby_fam.
DR Pfam; PF14645; Chibby; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..235
FT /note="Protein chibby homolog 3"
FT /id="PRO_0000340101"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 10
FT /note="Q -> E (in Ref. 2; BAB24904)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 235 AA; 26690 MW; E7B23A46755C4BE6 CRC64;
MADSKMKWGQ AWDSSLGTAT TSSSSATGSP SPFQNIRVPD TRAPRVAHTT FTLEAFECLA
ASQAGRLWKQ VRQFWVDHFS RRFSPRRPPL RHISSMSTFY LLDHRTRQAE LGLNYGEPRT
RLSDEAFVFR GGRWTPEGKR ASARTPLPSS TIPAWKPQVQ PIKSQVLLEE NNYLKLQQEL
LMDMLTETTA RMQLLEKKVD ADNNPAAPAR SWKRKMPKQR GAGVLIIQPR ALESR
