CC018_MOUSE
ID CC018_MOUSE Reviewed; 164 AA.
AC Q8BGK9; Q8BUH0;
DT 21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Uncharacterized protein C3orf18 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Cerebellum, Kidney, and Olfactory bulb;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AK032358; BAC27833.1; -; mRNA.
DR EMBL; AK032501; BAC27899.1; -; mRNA.
DR EMBL; AK043338; BAC31524.1; -; mRNA.
DR EMBL; AK085251; BAC39401.1; -; mRNA.
DR CCDS; CCDS23489.1; -.
DR RefSeq; NP_780695.1; NM_175486.3.
DR AlphaFoldDB; Q8BGK9; -.
DR SMR; Q8BGK9; -.
DR STRING; 10090.ENSMUSP00000047093; -.
DR PhosphoSitePlus; Q8BGK9; -.
DR MaxQB; Q8BGK9; -.
DR PaxDb; Q8BGK9; -.
DR PRIDE; Q8BGK9; -.
DR Antibodypedia; 2263; 92 antibodies from 16 providers.
DR DNASU; 235599; -.
DR Ensembl; ENSMUST00000042581; ENSMUSP00000047093; ENSMUSG00000037977.
DR GeneID; 235599; -.
DR KEGG; mmu:235599; -.
DR UCSC; uc009rlg.1; mouse.
DR MGI; MGI:2445137; 6430571L13Rik.
DR VEuPathDB; HostDB:ENSMUSG00000037977; -.
DR eggNOG; ENOG502RZ00; Eukaryota.
DR GeneTree; ENSGT00410000025882; -.
DR HOGENOM; CLU_134497_1_0_1; -.
DR InParanoid; Q8BGK9; -.
DR OMA; WFSSHPP; -.
DR OrthoDB; 1453896at2759; -.
DR PhylomeDB; Q8BGK9; -.
DR TreeFam; TF332764; -.
DR BioGRID-ORCS; 235599; 4 hits in 72 CRISPR screens.
DR PRO; PR:Q8BGK9; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q8BGK9; protein.
DR Bgee; ENSMUSG00000037977; Expressed in quadriceps femoris and 83 other tissues.
DR ExpressionAtlas; Q8BGK9; baseline and differential.
DR Genevisible; Q8BGK9; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR042351; C3orf18-like.
DR PANTHER; PTHR15868; PTHR15868; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..164
FT /note="Uncharacterized protein C3orf18 homolog"
FT /id="PRO_0000228842"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 106..130
FT /evidence="ECO:0000255"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 42
FT /note="E -> K (in Ref. 1; BAC39401)"
FT /evidence="ECO:0000305"
FT CONFLICT 52
FT /note="P -> S (in Ref. 1; BAC39401)"
FT /evidence="ECO:0000305"
FT CONFLICT 65..66
FT /note="LL -> FV (in Ref. 1; BAC39401)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 164 AA; 17721 MW; 8C5CA7F5B6BCA82E CRC64;
MNSRVPATQS WFSSHLPTTE PDLEPATAAE GSTTETATLS PETTSFNDTR IPDVAGGAAG
VGTMLLSFGI ITVIGLAVAM VLYIRKKKRL EKLRHQLMPM YNFDPTEEQD ELEQELLEHG
RDAASMQAAA SLQVTQGKST LPSQGPLQRP SRLVFTDVAN AIHA
