ID   YUEC_BACSU              Reviewed;         151 AA.
AC   O32100;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=ESX secretion system protein YueC {ECO:0000305};
GN   Name=yueC; OrderedLocusNames=BSU31850;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=168, and ATCC 6051;
RX   PubMed=23861817; DOI=10.1371/journal.pone.0067840;
RA   Baptista C., Barreto H.C., Sao-Jose C.;
RT   "High levels of DegU-P activate an Esat-6-like secretion system in Bacillus
RT   subtilis.";
RL   PLoS ONE 8:E67840-E67840(2013).
RN   [3]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=168 / PY79;
RX   PubMed=24798022; DOI=10.1371/journal.pone.0096267;
RA   Huppert L.A., Ramsdell T.L., Chase M.R., Sarracino D.A., Fortune S.M.,
RA   Burton B.M.;
RT   "The ESX system in Bacillus subtilis mediates protein secretion.";
RL   PLoS ONE 9:E96267-E96267(2014).
CC   -!- FUNCTION: Required for YukE secretion. Probable component or regulator
CC       of the ESX/ESAT-6-like secretion system (BsEss).
CC       {ECO:0000269|PubMed:23861817, ECO:0000269|PubMed:24798022}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000255}.
CC   -!- DISRUPTION PHENOTYPE: Cells lacking this gene are blocked in YukE
CC       secretion. {ECO:0000269|PubMed:23861817, ECO:0000269|PubMed:24798022}.
CC   -!- SIMILARITY: Belongs to the EssA family. {ECO:0000305}.
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DR   EMBL; AL009126; CAB15173.1; -; Genomic_DNA.
DR   PIR; D70007; D70007.
DR   RefSeq; NP_391063.1; NC_000964.3.
DR   RefSeq; WP_010886603.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; O32100; -.
DR   SMR; O32100; -.
DR   STRING; 224308.BSU31850; -.
DR   PaxDb; O32100; -.
DR   PRIDE; O32100; -.
DR   EnsemblBacteria; CAB15173; CAB15173; BSU_31850.
DR   GeneID; 936550; -.
DR   KEGG; bsu:BSU31850; -.
DR   PATRIC; fig|224308.43.peg.3334; -.
DR   eggNOG; ENOG5033EWP; Bacteria.
DR   OMA; YLHEDTY; -.
DR   BioCyc; BSUB:BSU31850-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018920; EssA/YueC.
DR   InterPro; IPR020212; YueC.
DR   Pfam; PF17355; DUF5383; 1.
DR   TIGRFAMs; TIGR03927; T7SS_EssA_Firm; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..151
FT                   /note="ESX secretion system protein YueC"
FT                   /id="PRO_0000049914"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   151 AA;  16915 MW;  B978E35213523A6F CRC64;
     MLSFSLFIPS AAAAQTEENT DVAPNQYEKK DIEIDTNYLH EDTYYEEKTE LPEEQKDITF
     DKPKDKDAEL IKDLFTSTNA EDSNTIAAQS KQLGITFAEK PMTKTSSTET EDEQETSSLL
     LPMIYVVLIL LGIAGIVFLI PKVTAQENKK A